ID W5MK25_LEPOC Unreviewed; 754 AA.
AC W5MK25;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Catenin alpha like 1 {ECO:0000313|Ensembl:ENSLOCP00000008734.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000008734.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000008734.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the vinculin/alpha-catenin family.
CC {ECO:0000256|ARBA:ARBA00008376}.
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DR EMBL; AHAT01018128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006635845.1; XM_006635782.2.
DR AlphaFoldDB; W5MK25; -.
DR STRING; 7918.ENSLOCP00000008734; -.
DR Ensembl; ENSLOCT00000008744.1; ENSLOCP00000008734.1; ENSLOCG00000007216.1.
DR GeneID; 102682989; -.
DR KEGG; loc:102682989; -.
DR CTD; 8727; -.
DR eggNOG; KOG3681; Eukaryota.
DR GeneTree; ENSGT01030000234543; -.
DR HOGENOM; CLU_015314_4_0_1; -.
DR InParanoid; W5MK25; -.
DR OMA; DQQKMAK; -.
DR OrthoDB; 2875237at2759; -.
DR Proteomes; UP000018468; Linkage group LG11.
DR Bgee; ENSLOCG00000007216; Expressed in ovary and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045296; F:cadherin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0007266; P:Rho protein signal transduction; IBA:GO_Central.
DR Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 4.
DR InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR InterPro; IPR001033; Alpha_catenin.
DR InterPro; IPR030045; CTNNAL1.
DR InterPro; IPR006077; Vinculin/catenin.
DR PANTHER; PTHR46342; ALPHA-CATULIN; 1.
DR PANTHER; PTHR46342:SF1; ALPHA-CATULIN; 1.
DR Pfam; PF01044; Vinculin; 2.
DR PRINTS; PR00805; ALPHACATENIN.
DR SUPFAM; SSF47220; alpha-catenin/vinculin-like; 3.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
SQ SEQUENCE 754 AA; 84642 MW; 41871E080B5E4286 CRC64;
MASSPCGSSS FDSGLEIKTR SVEQTLIPLV SQITTLINHK DKPKKSEKTL RAIQRVGQAV
NVAVGRFVTV GEAIAMENED LKEEMNFACY EARRAGDSIA QLTDVVSSEH PESDGRSTIF
SDKTGMVKAA RMLLSSVTKV LVLADRIVIK QIVTSRNKVL TTLEQLEKVG SFQEFVQIFS
QFGNEMVEFA HLTGDRQNDL KDEKKKSRMA AARAVLEKCT MMLLTASKTC LRHPDCESAR
INKDAVFHRM RFALEQVIEI VTDARPNGET EVQTISIYTG IRDFKNKVEG LREEQYSMSQ
ESLLAILEGI LEHTEDFTDS AYTSHEHRER ILELSQLARQ ELEQLVTVWI QAQSYKVKEV
TEEMELSILK TCQSLNELRR ELHKAAVGLA ADLLKYHADH VVLKALKVSG GEGNLETVAE
YSCKLTEQKE QLVETCRLLR HVSGTEPLEI TCIHAEDTFQ VIGPQIISAA QTLALHPSSK
IAKENLDVFC EAWESQLNDM SILLREINDV FEGRRGDKRT YLSLPRPGKH SANLKTVKAV
KLDAEEQSTI AKLGLELRLL TSDVDSESDK WEDQEHEIVR QGQSMSSMAY SMYLFTRGEG
LLKTTQDLFH QAEVFSEEGF KLCSTLQAFS SQLGDDEKSL IVSEKEKLGA LCQQLQVTAK
TPVQGKNATF MKVDSSIQNT KNIMTVVVYL LPVCYKLIRK YMSEKSSLGS PQSWREKQLP
TPVNEDALDR KNANGFGVKS LEHHMSNLTF LESK
//
