ID W5ML04_LEPOC Unreviewed; 1253 AA.
AC W5ML04;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Sushi domain-containing protein {ECO:0000259|PROSITE:PS50923};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000009063.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000009063.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AHAT01016031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016032; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016033; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016034; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01016040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5ML04; -.
DR STRING; 7918.ENSLOCP00000009063; -.
DR Ensembl; ENSLOCT00000009074.1; ENSLOCP00000009063.1; ENSLOCG00000007460.1.
DR eggNOG; ENOG502QVSB; Eukaryota.
DR GeneTree; ENSGT00940000154386; -.
DR HOGENOM; CLU_003511_0_0_1; -.
DR InParanoid; W5ML04; -.
DR OMA; CIKICEI; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000007460; Expressed in liver and 10 other cell types or tissues.
DR CDD; cd00033; CCP; 15.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 20.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45785:SF7; COMPLEMENT FACTOR H; 1.
DR PANTHER; PTHR45785; COMPLEMENT FACTOR H-RELATED; 1.
DR Pfam; PF00084; Sushi; 16.
DR SMART; SM00032; CCP; 19.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 20.
DR PROSITE; PS50923; SUSHI; 17.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1253
FT /note="Sushi domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004866418"
FT DOMAIN 20..81
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 82..142
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 143..203
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 204..260
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 261..325
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 390..447
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 450..509
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 511..568
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 571..628
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 631..688
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 694..754
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 825..882
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 885..943
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 944..1004
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1005..1070
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1071..1129
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1132..1190
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 52..79
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 113..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 145..188
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 263..306
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 513..556
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 887..930
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1073..1116
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1134..1177
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 1253 AA; 142789 MW; 23A72EC32EDC79E9 CRC64;
MKLKFILTLW IFIFAVVLVE GCDNPPDMEN AFIPEENKKA VYDNGDVVKY QCHAGFISRG
SVQYKCVNDV WERVGFRTCQ PKPCGHPGDT LNAAFRLIKG TDFVFGSTVQ YICNEGYQMA
SRISTRNCRE NGWDNDLPHC EVVTCVPEEL TEGVTSNVGS DPVTYGGVIQ FQCNLPNSKL
DGSEEIFCTA NGQWSSKFPK CIEITCDAPT LTHGTILNDQ PTYRNNDDLR YNCDKGYKPL
ERPIAKCTKR GWSPQPQCQE VTCEKPVNSD FGDYSKSIYH VGEQAILKCQ SGYKTITNTR
SVTLTCTDNW TSETKGWSMN PYCYPITCQR PRGKGLRVKE VDSWGVYPRA VFNYDQEIVY
FCDSGYKPET HQRAKCKFDG FEPEPICHEI VCDLPIIENG RVTEKAKTQY KHNQGLNYQC
DSNFEPERPQ RLTCGKNGWD KLPSCTAKHG MCTKPNLPNG YFSSKKEVYD NGSNVLYACS
PKYKPSTEGW WGTIQCISGQ WSETPQCIPE DSCATLPTVI NAKVKDNKSS FFPHGSSVHY
ECLEPSEFEK ESFATCTEGK WKVPNCILRV KYCETPPRVE HAVIMEPFQR FYRDGSRVEF
RCEETYEIKV EYMFCEKGKW SQKPQCILQT KPCDEPPYVD NAISPPRQSV YENGSKVEYK
CHTNYKIKGD KDVFCENGQW SQIPECTLFE RTHDNCGEPP ALLNGDTISE RPQNNVYKHG
DKVKYQCTRF YKISGSSEIT CQQGQWTKLP TCHLTDMRSS SKVPKKGGTL SGHHQKEVYD
SGSTVYYACS PKYKPLTEGW WGTTQCINGQ WSDSPQCISF RARSYHCDAP PHIEHAVIIA
PYQRFYQNGS RVEFRCEETY EIKGEYIFCE NGEWSQKPEC ILQTKLCDAP PHVEHATIIG
PLLNEYNDGS QVEYSCEETH EIQGQKLIFC EKGQWSQIPE CINDNCEDPP ALENGDTISE
RPQNNVYKHG DKVKYQCKQF YKMSGSSDIT CQRGQWTKLP TCLRKDCVDY KKTAKITPHY
PFKKTVYTSK PRTSAHCPEC ASPDTHLNGE SQIFCTTNGN WSSPFPTCKV LSCGSPPDVH
KGKLLSPRKK SYREGEKVEY ECENKFHFQG QSYVQCRRGR WTTTPVCCLA PTFCGQPPVV
TNADIEGWTK SSYDSGDRVT YRCQKFYEVE GSNTITCTRG EWTTLPKCLE PCTVTLDDMK
RNNLRLRFRE SELVFIKHNE YCEFACIDGK SLKGNNPLRL KCNDGKVNLP VCG
//
