ID W5MLL2_LEPOC Unreviewed; 429 AA.
AC W5MLL2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Forkhead box J1b {ECO:0000313|Ensembl:ENSLOCP00000009271.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000009271.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000009271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; AHAT01013653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01013654; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01013655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000009271; -.
DR Ensembl; ENSLOCT00000009282.1; ENSLOCP00000009271.1; ENSLOCG00000007642.1.
DR eggNOG; KOG2294; Eukaryota.
DR GeneTree; ENSGT00940000164514; -.
DR InParanoid; W5MLL2; -.
DR OMA; RRMPDIH; -.
DR Proteomes; UP000018468; Linkage group LG13.
DR Bgee; ENSLOCG00000007642; Expressed in larva and 5 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0003146; P:heart jogging; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR047513; FOXJ1.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46805; FORKHEAD BOX PROTEIN J1; 1.
DR PANTHER; PTHR46805:SF3; FORKHEAD BOX PROTEIN J1-B; 1.
DR Pfam; PF00250; Forkhead; 1.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 142..238
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 142..238
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 54..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 240..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 48014 MW; E8981B344CAF736A CRC64;
MPVLMSPEIA TKFKEKWMLL HPDEQDNISG SMNLDDSLTS LQWLQDFSIL SANLERPPSS
GCSRDPDSEQ STRRSLAVQD SYSLRSTGDS AIVTPHRATV RSPLTACVAL ECPPAFSLIP
YHLLKSNKHQ QYFQRKRQKV VRGPQSYPLT IKHLFKYLEK VQKHNVKMMC NYLTKRTCYN
TASHPAVLHN SIRHNLSLNK CFMKVPRQKD EPGKGGFWQI DPQYADMFVN GVFKRRRMPA
AHFSAPRQSK MSPVPEASYS PAXGSKRKQP SPKRSAKLGR GPQSPLLAPE AEALKGDFDW
ASVFDDVFSG GGGGGTFEDL DLNAALSSLG CDLDPGLQGR HPGGGALKWG FAELAGGLVG
TPQPPLAPQQ QHLEDWALFS EQQQQQQHHP WEELREDAQA IPLAFDQSFN FCEGLFTEMQ
PWDRVEAYL
//
