ID W5MN48_LEPOC Unreviewed; 322 AA.
AC W5MN48;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Cleavage and polyadenylation factor I subunit 1 {ECO:0000313|Ensembl:ENSLOCP00000009807.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000009807.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000009807.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01027169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01027170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MN48; -.
DR STRING; 7918.ENSLOCP00000009807; -.
DR Ensembl; ENSLOCT00000009818.1; ENSLOCP00000009807.1; ENSLOCG00000008074.1.
DR eggNOG; KOG2749; Eukaryota.
DR GeneTree; ENSGT00940000153668; -.
DR HOGENOM; CLU_018195_1_0_1; -.
DR InParanoid; W5MN48; -.
DR OMA; GENQWER; -.
DR Proteomes; UP000018468; Linkage group LG9.
DR Bgee; ENSLOCG00000008074; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0051736; F:ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; IEA:Ensembl.
DR GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IBA:GO_Central.
DR GO; GO:0007420; P:brain development; IEA:Ensembl.
DR GO; GO:0006378; P:mRNA polyadenylation; IBA:GO_Central.
DR GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.330; Pre-mRNA cleavage complex subunit Clp1, C-terminal domain; 1.
DR InterPro; IPR045116; Clp1/Grc3.
DR InterPro; IPR010655; Clp1_C.
DR InterPro; IPR038238; Clp1_C_sf.
DR InterPro; IPR032319; CLP1_P.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR PANTHER; PTHR12755:SF6; POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1; 1.
DR Pfam; PF06807; Clp1; 1.
DR Pfam; PF16575; CLP1_P; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 6..192
FT /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT /evidence="ECO:0000259|Pfam:PF16575"
FT DOMAIN 199..320
FT /note="Pre-mRNA cleavage complex subunit Clp1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06807"
SQ SEQUENCE 322 AA; 34851 MW; 734F5A65218F5D9E CRC64;
QVMVVGPTDV GKSTLCRLLL SWAVRVGRRP TLVELDVGQS GVSVPGTVSA LCIERPADIE
EGFSVQAPLV YHFGSTTPGT NIKLYNKLTS CLAEVFSQRC EVNRRASVGG CVINTCGWVK
GAGYQALVHC ASAFEVDVVL VLDQERLYNE LKRDLPHFVK VVLLPKSGGV VERSKECRRE
ARDEKIREYF YGFRGVSFFP HAFDVRFSDV RIYKIGAPSI PDSCLPLGMS QDDTQLKLVP
VTPGRDLAHH VLSVSCGGEE GGAEAGGGKA AGGGILDSPV CGFIVVTAVD TQNQVMTVLS
PAPRPLPRHV LLIMDIRFID LK
//
