ID W5MPY9_LEPOC Unreviewed; 871 AA.
AC W5MPY9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Seizure related 6 homolog (mouse)-like {ECO:0000313|Ensembl:ENSLOCP00000010448.1};
GN Name=SEZ6L {ECO:0000313|Ensembl:ENSLOCP00000010448.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000010448.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000010448.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AHAT01005306; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01005307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01005308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01005309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01005310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MPY9; -.
DR STRING; 7918.ENSLOCP00000010448; -.
DR Ensembl; ENSLOCT00000010462.1; ENSLOCP00000010448.1; ENSLOCG00000008591.1.
DR eggNOG; ENOG502QVYR; Eukaryota.
DR GeneTree; ENSGT00940000158873; -.
DR HOGENOM; CLU_011474_1_0_1; -.
DR InParanoid; W5MPY9; -.
DR OMA; NRDCFGN; -.
DR Proteomes; UP000018468; Linkage group LG20.
DR Bgee; ENSLOCG00000008591; Expressed in camera-type eye and 6 other cell types or tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043025; C:neuronal cell body; IBA:GO_Central.
DR GO; GO:0090036; P:regulation of protein kinase C signaling; IBA:GO_Central.
DR GO; GO:0060074; P:synapse maturation; IBA:GO_Central.
DR CDD; cd00033; CCP; 5.
DR CDD; cd00041; CUB; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF8; SEIZURE 6-LIKE PROTEIN; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00084; Sushi; 5.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00042; CUB; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50923; SUSHI; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 801..823
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..291
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 293..405
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 408..469
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 471..582
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 586..645
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 647..710
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 714..775
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 51..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 616..643
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 871 AA; 94712 MW; 33067F84A2E9B5CD CRC64;
QELLESVLAE RDFLLSKKGA AFPTALPGDL NPKRILAEVG RRGGILSSKQ ISAARKRLRP
HETSAAPQLL TPGPTDREPT RASVSQWHFT TGTPMPSVPS LLTADIPPTL TPGNEIAVSR
CSVGFSDPEG HIDSSDDPPP PSGSLLECTY TVTVYTGYGV KNKVKSVNLS EGEQLSIRGV
DEGGVLLVLA NETLLVEGQV IRSPTNTISV FFRTFPEGGV GTFQLHYQIF RLSCALPRRP
HHGDVSVLDL HAGGMAKFRC HLGYHLQGEP QLTCLNASRP HWSSHEPTCR ALCGGAVQNA
TVGRVLSPSP STSTNDSTAI SCSWTLEAPA GQRLHLHLER LALGPTDRLV LWSGLDAGSV
VLFDSGRGGP IPFEGVISEG PAVRVQFTSD LPQPPGGFNI RYEAFERGHC YEPYLQNGNF
TTSDPGYGVG AVVQFSCAPG HSLEQGPPVI ECVNDRDPYW NDTEPLCKAL CGGDLSGPSG
VILSPNWPDA YGEGEDCSWR IHVDEDRRIL LDVQLLNLSD SDIVTILDGD EVTTRILGQY
IGGTSPFKLS SSTPDLTIQF HSDPAGLLFG KGEGFIINYM EVSRNDSCSD LPEIQNGWKT
TSHAALVRGA RITYQCDPGY DLVGRETLTC QWDLSWSSQP PFCEKIMYCS DPGHVEHATR
TLSDPKLLVG TTIQYTCNPG YVLQGGAILT CYGREPGTPV WTSRLPRCVS EESVSCENPG
LPENGYQILY KRLYLPGESL TFMCYQGYEL IGEIAIKCIL GNPSYWSGPL PLCRASQDCF
DNHALEVAEA AADSSLDGGN MALAIFILVL LLSVLLGGAY VYVTRCRYHS HLRLPLMYTH
PYSQITVETE FDNPIYETGG LQDTREYEVS I
//
