ID W5MUG9_LEPOC Unreviewed; 480 AA.
AC W5MUG9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Butyrophilin subfamily 1 member A1-like {ECO:0000313|Ensembl:ENSLOCP00000012028.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000012028.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000012028.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; AHAT01012870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MUG9; -.
DR STRING; 7918.ENSLOCP00000012028; -.
DR Ensembl; ENSLOCT00000012049.1; ENSLOCP00000012028.1; ENSLOCG00000009842.1.
DR eggNOG; ENOG502QSRZ; Eukaryota.
DR GeneTree; ENSGT01070000253822; -.
DR InParanoid; W5MUG9; -.
DR OMA; DMEVTWF; -.
DR Proteomes; UP000018468; Linkage group LG14.
DR Bgee; ENSLOCG00000009842; Expressed in zone of skin and 11 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0005102; F:signaling receptor binding; IBA:GO_Central.
DR GO; GO:0001817; P:regulation of cytokine production; IBA:GO_Central.
DR GO; GO:0050852; P:T cell receptor signaling pathway; IBA:GO_Central.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 135..216
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 299..480
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 480 AA; 55126 MW; AB0C01B66F10EEE9 CRC64;
MLIFLLQLSV SRSEKFNVVG PTAPVVVSPG EDTVLPCYLS PNISAELLEI RWFRENYDAP
VCFYQNHTYN HDGQSPPYKG RAELFLDELP KGNVSLKLRD VRLSDNGQYN CLVESKQHYE
DALIDLAIRV QGSGPLLVYI SSMEDGRTWL LCTSEGWFSE PAVIWIDRNG KETTSLSNTT
VERNSQGLFN VSSYIPVSQD SQILSCLVRS VSPELDWGSQ LHIPRDFLPE PSGWMVTLFL
TATVIAAASA LLVFQWRRMD SRQIGKVQSK RVKSKEANEC IQNKTSRRLQ PFLYFGENWV
SKGQVNLDMY KKETKETDVT LDPDTAHYEL TLSEDRKRVR WEEKQDVPDK AKRLGSGPCV
LSREGFTSGR HYWEVEVTDL WRIGVTRESA ERKGRFSFSP QCGYWVLECN SSHLRNQPRM
VGVCVDIDER NVSFYTVESR THIYKFTDMV FNQGEKIYPV FWTWDENKEL VLLPLVSCGY
//
