ID W5MVS1_LEPOC Unreviewed; 599 AA.
AC W5MVS1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Kelch repeat and BTB domain containing 8 {ECO:0000313|Ensembl:ENSLOCP00000012480.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000012480.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000012480.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01020693; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006630686.1; XM_006630623.2.
DR AlphaFoldDB; W5MVS1; -.
DR STRING; 7918.ENSLOCP00000012480; -.
DR Ensembl; ENSLOCT00000012501.1; ENSLOCP00000012480.1; ENSLOCG00000010195.1.
DR GeneID; 102697877; -.
DR KEGG; loc:102697877; -.
DR CTD; 84541; -.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000158653; -.
DR HOGENOM; CLU_004253_14_6_1; -.
DR InParanoid; W5MVS1; -.
DR OMA; FWMYDHA; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000010195; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF433; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 46..114
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 599 AA; 68717 MW; EC86931850CD1E39 CRC64;
MAAGGDIGKL LQNGTAANSN YNGMDPLHAC KILQQLKSLY DEGQLTDIVV EVDHGKTFSC
HRNVLAAISP YFRSMFTSGL TESTQRKIKI LGIESESMHL VLEYAYTSKV TLSESNVQAL
FTAASIFHIP SLQDQCALFM ISRLDPQNCI GVFMFADAYG HQELKEKSQD YIRKKFLCVV
NEQEFLHMTK EQLVSVLDND DLNVEKEEHV YNSIIKWLEH DRDRREADLA EVFAKCIRLP
LLEDSFLKKI PPVFAQALEK EWADKGKFNG TNGCPLRLGM TALEMIICFD AAHKHSGKKQ
TVPCLDTIAG KVFKLCKPPN DLREVGLLVS SENDIYIAGG YRPSNSEVSI DHKAESDFWM
YEHSGNRWIP KSPMLRARIG CRLVHCCGKL YALGGRVYEG DGRNALKSVE CYDSRDNCWT
SVSAMPVAME FHSAVEYKDK IFVLQGEYFF CYDPRKDYWG HLTPMRIPRS QGLGVVYKNC
IYYIAGICKN HQRTFVVETY DIERNMWIRK KDLPFDQATS PYIKVLLLHG KLHLFVRATQ
VTVEEHVFRT SRKNSLYQYN EKTDQWIKMY ETPDRLWDLG RHFECVVAKL YPQCLQKVL
//
