ID W5MX64_LEPOC Unreviewed; 3934 AA.
AC W5MX64;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=A-kinase anchoring protein 9 {ECO:0000313|Ensembl:ENSLOCP00000012973.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000012973.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000012973.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR EMBL; AHAT01004647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSLOCT00000013000.1; ENSLOCP00000012973.1; ENSLOCG00000010582.1.
DR GeneTree; ENSGT00730000110871; -.
DR Proteomes; UP000018468; Linkage group LG11.
DR Bgee; ENSLOCG00000010582; Expressed in camera-type eye and 13 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR028745; AKAP9/Pericentrin.
DR InterPro; IPR019528; PACT_domain.
DR PANTHER; PTHR44981:SF1; A-KINASE ANCHOR PROTEIN 9; 1.
DR PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR Pfam; PF10495; PACT_coil_coil; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 3731..3812
FT /note="Pericentrin/AKAP-450 centrosomal targeting"
FT /evidence="ECO:0000259|Pfam:PF10495"
FT REGION 15..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1474..1515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1664..1725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2777..2808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3274..3300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3316..3360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3468..3494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3513..3532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3588..3608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3816..3873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 133..217
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 260..361
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 391..511
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 543..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 660..766
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 798..875
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 912..960
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1038..1100
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1136..1170
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1258..1379
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1516..1543
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1876..2268
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2301..2392
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2428..2567
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2621..2669
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2701..2763
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2877..2904
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3624..3651
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3678..3705
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 32..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1698..1717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2785..2808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3320..3346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3588..3602
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3816..3840
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3847..3862
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3934 AA; 451258 MW; 90F802EEB6C846C0 CRC64;
LLTHLCVLQL AEYRQRKAQA DGQKKTKKKK RPAGAKDGEP SRAEERGEAG AHSADPTVSR
SLRSGDTIRQ DQTYTIEPES EVSTTADDYT SEVNGCLEVA VNTVESKDFI REEEVHVSAS
HSEHEAHSSQ TRLQIMEDEL AAKQQAVEEL SRELEEMRAA YGSEGLQQLQ EFEAAIKQRD
GIITQLTANL QQARKEKDEI MREFLELTDQ SQKLQIQFQQ LQAGETLRNT SHSSTAADLL
QAKQQILMYQ QQTEEKDLQL KGCQRKNDEQ QMQISQLQER VKETEMLSSK QDESFTQRLR
EQEKLIAGQQ KQITEHEVTV TRLKEELSIS EKSLQDLMKQ LVEKQQELET FQNELTSSKQ
REKMSSDEIK QLMGTVEELQ KRNHRGNQAE SEIVQRMKGD MERKMDQLQA EMDEMYGQQI
VQMKQELRKQ HLEEINRLTA QHRSELKVLS LQSSENGADV EQINLLNMKI IELQQKLKEA
QMQKDKVHQE LTQVAEEKLN LQSQVEDLLQ DLRFVRGKVQ RASQSISDQE HKLSEVGQLH
ATISDLQTQL TAAAEATKEL ETKHESEITN YKIKLEMLER EKDAVLDRMA ESQEAELDRL
RTQLLFSHEE ELTKLREDLQ RESQVNIESL KDEMSLKHKQ VLESMRMSFE EQLHVVKLEK
EKLAADREAL LSEISQMKDD LNHSLEDPMS KGMALKLEEL QTEICELRKE EKEKYSLERE
IHELSKKNEL LEKETKEREV TLGQKIKKLE SEKNYLEETN EAMRQKMKSV DLDFDIKDNS
SALSSDIAVL PSRMHQQIES LTLENKKLSK QITELKENLE RQTNTFSFAE RNFEVNYQEL
KDEYTCLVKV KAELEERLLK EAGEHETELN HLRSQVQLLQ AGKEQLGGTV EVSQVRNTED
FIDGGEVVEK DTTELMEKLE IAQREKKELS LRLSEASEQL NLKQNEIEQL KDELMSVTDI
NKQILASYED LRRGQGAQGK TAGQRQEQQT WEIVQTTAVT TDQATGRELC THANHLHQIE
AFEKKTTVLE RDHIQEQQSA LAHENETLSA ELQELRGKPV AETPVAAALR ADRDQLQQQL
DALRAKQDEL RLQMEAQRIS LSQICAAQLE LLRESLLAEK EACLHSLEES LVGRHAQEVQ
QLHEKHQQEL QHLKEQKADY EAESRSSKHQ RFISMVSEEC TQLILLYKER FMQKQKSLLV
TGDITLKTEE RPFMEQMGSN ISKLCFFTLI LELYTSLHML KDRILQECNR LTELQSLLTS
DCNKLEELQT AYDELRHQSE KEIASLRMQI DSSRASSQDL NGNLYINLKE QLKVRSAHLE
EVEKLKTEFH QRQAQLEEQH LQEIERLRVY YQQQARDLED RYTTELVLLQ QRLQEAQCRA
YSHYESISSE AQLFEQKEMQ SIEELKNSEN NEIYIYNFQL DDIELEVALN YPLKNIQELE
KRHKERTEEE VAKVIVQMSV EFAQQTELAR LNKQARETTT KMQTLAGDPD GEGEAEMDPS
SEEPGLALEQ KNKDSERRLL EEKAALSKQL QEKTAEILTL TKQLQQTRGA PLMLDKEGQF
SDTEGGSPKH PEDTGIILPL ESVITQEPVL PESKVATAGL AEDQCQNQKQ EHLQAAQALR
VAHTQPLDRQ QEEQVSRRAE LDSWGTQLDQ VRLPANHEAT VILQTSSVQR AKARREGPET
VRQEGYGPAL QSRSTQTEQN EEENKQGDEE KKTDPETSAE GPGFSNEFLK TKIKNVLRRA
NERLRQVLRD VLKTTAAAEE TIGRHVEGLL DASGRGQPQK PFKLDCHRDD SLPSFIFEDQ
LSIVLLIVST FTEDASSESC YGSEAGRGDG SVWSGETEEG LEMSQRLTDG LFQGADLQLE
NEECLMSISS RLQGAVEKLL EAITETTNQL EHAKVTQTEL MRESFRHNAE ISELVRQQEE
LQERLDEEAK AKEQLALELH RAEGLIDGYT EEKAAMEEQV RQKEELLQHL EQELRVTGSR
LLELEQERQQ MQQERELLSR QQAAMRDAAG PRELCLLEET EKLMKEKVEV QRQAEKESGD
LLQQVKALEV ELEEQVNRAV ELEQAKAAES ADLRQQIQAL EKQLEKNRKF LDEQAIDREH
ERDVFQQEIQ KLEQQLKSPQ KLQPSSEQRN RKVEQLTSQL KEKADRCSEL LLHVEQLDRD
VQERNEEIEK LECRIRELEQ ALIVSTERLQ KVEERKQYAS VDAPGEMTLE VQLQTEREAL
DRKEKEICNL EEQLEQFREE LENKNEEVQQ LHMQMEIQRK ELSTQQQELE HGNTLLKNEV
ELLKKSHCDS EDVSVEDRVR ISNLTKVMED KDREIALLNE QLFKLQQLEN VPDNKEIEEK
DELLKELRSE IECLRSEQER LKKKSEDEVE QLNEVIEKLQ QELSKIEHKT AEEYLPDSED
PLSQQHLLER ILERDYPKGQ DEKVCDELSL VKAEFEELKM KMEQTNQELD TLKSDHIVLL
EKYDCLLKES SDSSTEKKNE REEELEEIRL KMEQAFIQAE LKALEQSANS RVADLNAKVE
DLEVSVEEKD SELRFCRLQV DQTRAEAQTL QRKILQLEDA LREKVAAALV SQAQLGAFLQ
QSKEHTKELY SQIEELQGHP SEHPGQVGRT EESEKTAENF AVLLTQKIID LENELTDVQK
DQDLQKQLLL GSEEELEEYE KRLVRLMNLL EQISKWGAEK QETLTKKASG SAGEEADRAA
VSQLAQELQE VRAEAAATKE ELSSSRERAD KLQEELQVRD LSVAQLQEDL QRVKEALAGS
ERELALHTVN KEAGAPEGEL DFISDKNNGT ITKDKASLPR RSSASQTDKP VVVNGSVQTL
PVACRDAEVQ ADLVKPGAAR SEDIAEVISQ YTEKIGQMQD LHAAEIMDME TRHISESETL
KRDLEMLREE CQALNALVDK LRTAEESSYI SLSIYFCKNS SSDWSQRLGY DIGSQNQEFR
STPEGARRDN EVRQLAEDML PDKIKSLLRE VHKEGMQVLS LSELPFSDVE PTGAGEPSQS
WQRERDALLA AVESLKTLIT TMQAHRGPEP LAGNIAAEQS ADWRGELLHA VQQVFLKERG
VLTSALKTHL EMLDTSDIVV HLNQLECRLD EQDTRHREAM EFLQGADRQS LLTDVRQLQA
QLHSTQPGQS RRETDGQSLL ASGKGLKKYR ISDIKSGHAQ NQQAAEGKEA LLSERMVLAD
LKNELAQTRL ELETTLAAQH KRLKELEALR TEVSEKAAEV DRLNDALAEE QRKARELQWA
FEKEKCKSER TKERENEELE DLKLALADQK HRVGQLAESL EQEREAAESE RARQQARLTH
EQGRVAELQV QLESEKARAQ ELSGALERER GLHSRRRQQQ SPQRRAEEEE EEEEGEQRVE
ELLADLQRQL DEKHSRIAQL VGDVERHKLE AAQVGQQWDE ERRSQRLAAQ REREALQLAQ
DKLQQLQGKA QELQRQLDRE RQQVLRLQQE RDRLGDSVRD LQDTARLSEA ARDSAQPQHP
DARAQNPWKA DLQPSDRTRD WVLQQKMSEV LTAGSSSLPL KEGAASQAAP TDSRLLDSVI
PKLQLIASKI RSLASKASSS VPFEELDSES LVWLLNSVQD VVSQLQQLPP VPPVPESPPV
PSGDPSSSLA ERLLRQNAEL TGFVSRLTEE KNDLRNALIK LEEELRRYRH RGLAGGDCTN
RSPADNQDAI DAILVSDREA WNREKASLEK SLQQAEAEVS RLRSELRTDS LCRDMAGSDS
DSTALKRIYG KYLRAESFRK ALIYQKKYLL LLLGGFQECE EATLSLIARM GGRPSYTNLE
VITHHRRGFT RFRSVVRVSI ALSRMKFLVR RWQRATGSGS SPASSVNRNG FGQITGNEVR
TDSPYLHPEV YGERRASSRG RSGRESPRST LSVHHRYQTT AEAPGSLACS HLQNYDPDRA
LTDYISRLEA LQRRLGSVQS GSTSYAPLHY GIRR
//
