ID W5MY70_LEPOC Unreviewed; 539 AA.
AC W5MY70;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Solute carrier family 23 member 3 {ECO:0000313|Ensembl:ENSLOCP00000013329.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000013329.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000013329.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; AHAT01034474; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01034475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MY70; -.
DR STRING; 7918.ENSLOCP00000013329; -.
DR Ensembl; ENSLOCT00000013357.1; ENSLOCP00000013329.1; ENSLOCG00000010877.1.
DR eggNOG; KOG1292; Eukaryota.
DR GeneTree; ENSGT00950000182953; -.
DR HOGENOM; CLU_017959_5_4_1; -.
DR InParanoid; W5MY70; -.
DR OMA; LTWGLSC; -.
DR Proteomes; UP000018468; Linkage group LG12.
DR Bgee; ENSLOCG00000010877; Expressed in embryo and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF57; SOLUTE CARRIER FAMILY 23 MEMBER 3; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 518..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 57335 MW; 310E8E8BD79BE097 CRC64;
MATSLFSSGI STLLQTTLGT RLPLIQAPSM EFLIPAIILT SQEEGHHHGN GSEVTCSGPW
CGTKEDTITW NKPIRELQGA VVAAGLVQVL LGISGLSGLI LWHCGPLVIA PMLCIIGFSI
YKEAALLCSS HWGIATLIVL LIVILSQHLH DCFFPAWGTC VPEESPKPSY YPACRMLSVL
LPLLCVWIIF VPLEITGVYP LKHPEELSQL SRPINLTYQV PWLRLPIPGG GDLPLLTPRC
ITAGIAAALS AAISSQGCYM VTARLLEAPP PPPGACNRGL ASEGLGSIIA GMLGSVGGTS
TSVPNACALG LNQCGSRQTI QLSALLCVCL GVSPKLTQML TTIPLAVHGG VLSVTYAIAV
ATGITYFQYT HMDSGRNIFN IGFTVFMALL APHWFNRNPS IISTGVSSLD VFIQSLLTMP
VFLVGVLAFL LDNTVSGTPV ERGLHAGVTG KVFKGAEALV RKIPGYSDQL ALVYDPPFLV
RRLLNHPWLQ AFPFCACGLL DGKTAKAEVT LPEEATDLLV PSSQQSPRSM NNIPSVSEC
//
