ID W5MYD7_LEPOC Unreviewed; 1234 AA.
AC W5MYD7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Protein phosphatase 1 regulatory subunit 9A {ECO:0000313|Ensembl:ENSLOCP00000013396.1};
GN Name=PPP1R9A {ECO:0000313|Ensembl:ENSLOCP00000013396.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000013396.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000013396.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHAT01004632; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01004633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01004634; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015213565.1; XM_015358079.1.
DR AlphaFoldDB; W5MYD7; -.
DR Ensembl; ENSLOCT00000013425.1; ENSLOCP00000013396.1; ENSLOCG00000010917.1.
DR GeneID; 102689540; -.
DR KEGG; loc:102689540; -.
DR CTD; 55607; -.
DR GeneTree; ENSGT00940000155538; -.
DR HOGENOM; CLU_007401_0_0_1; -.
DR OrthoDB; 2911512at2759; -.
DR Proteomes; UP000018468; Linkage group LG11.
DR Bgee; ENSLOCG00000010917; Expressed in camera-type eye and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd09512; SAM_Neurabin-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR040645; Neurabin-1/2_PDZ.
DR InterPro; IPR043446; Neurabin-like.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR16154; NEURABIN; 1.
DR PANTHER; PTHR16154:SF22; NEURABIN-1; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF17817; PDZ_5; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 502..590
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1125..1188
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 598..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 678..821
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1182..1219
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 8..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 824..838
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..856
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..979
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1013..1034
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1234 AA; 136070 MW; EC46BE9163008BAE CRC64;
MMKTEASGER STLRSASPHR NAYRTEFQAL KNAFDQPRRD GDPKPKEACE KPPQARGRQY
GSNVNRIKNM FMQMGMGPNE NTGPPSKTKG KEGSSPQKIR RPKPSVDKTG ESAVKLQATV
SERVSRFDTS RDGTAHSKFS ETRKMFEQTI RETSQSSRSS SGKDRKGSHE HLDEWKGMRS
NLGSTDSLDS LCSRTEASSP TVSQLSAVFE NADQQNAAAW KKTGSKGLCS PDGSQRQTEL
SEDDVSWQQS PPHRRHKRHG QKQAIPLSSS SEDLLSPSPV SETADEGKGI SSVSQQRNEH
EKEMEYNQGN AEDFRADAAS DCGVQRQMGA VAGSEVDGVY SDSAVSEPSA GNEHRTQIPK
MPPSQLNEQA EGPVLADSAW VSDEHAKDPS EGYTGSEKAI GTSESAMYYQ GWGESCTDPE
DQACSEENSH YEPDSEIVEI PGLPEEEDVA SNRKIRFSTA PIMVFKTYSN EDYDRRNDEV
DPVAASAEYE LEKRVEKLDL FPVDLEKDED GLGISIIGMG VGADAGLEKL GIFVKTVIEG
GAAQKDGRIK VNDQIVEVDS ISLVGVTQNF AATVLRNTEG VVRFLIGREQ PGQVSEVAQL
ISQTLEQERR QREMLEQHYV QYDADDDETG QYATDDEDED MVPDITGGDM AIEVFDLPET
ADMFSPTEMD ATKLSHKFRE LQIKHAVTEA EIQKLKSKLQ STENERVRWE REKTQLQKSI
DDNKERMLKL EGYWIEAQTL CHTVNEHLKD TQSQYQALEK KYNKAKKLIK DFQQKELDFV
KREQVEKRKF EDAEKVHLIE IQGLQAQISN LEAELLNLMK QSGTQVNNNN NSAERISTLG
REEPSESTED ALRTRGAVAD GDFAEAVPET ERLDSEALKA RAQLSVKSRR GRPSRPRPRG
SLSSTDGEDG LERKTAEGGS SPLHSSMPAL PSSPKPTSRA LDPGTSSSPP AQGGGASTAV
LEDSPTSSPS RSCSSEASPL HHPQLDREDE GSLSPLISSP SVGPLGKTKR KLIDLGSPAR
HSPGREKKDK DSSRLSSGNS STEPSSENSP EKHKAKNVGL NNDVSASSVS SADFSGLVAE
PKITGRSHSL ALSSDESLEM IDDEILDDSH SPKHQQWQNR AVLEWSCQQV SHWLMGLNLE
QYVPEFTAKG INGEQLLQLD GRKLKSLGVV SSQDRALIKK KLKDLRAVVD KALKTREKLE
KHREKLWKKE QELLQREAKK TGKTSGGPAE GSAE
//
