ID   W5MYU0_LEPOC            Unreviewed;       776 AA.
AC   W5MYU0;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000013549.1, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000013549.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AHAT01017643; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; W5MYU0; -.
DR   Ensembl; ENSLOCT00000013578.1; ENSLOCP00000013549.1; ENSLOCG00000011035.1.
DR   GeneTree; ENSGT01100000263481; -.
DR   HOGENOM; CLU_000680_32_4_1; -.
DR   Proteomes; UP000018468; Linkage group LG9.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd09076; L1-EN; 1.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR47027; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00078; RVT_1; 2.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT   DOMAIN          440..664
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   776 AA;  89826 MW;  0A4B56D5DD5EE02C CRC64;
     PDADAACDER KNLHCTKTHK ISTWNIRGMS QGKLDIIKRE MIRLNIDLLG ISELHRKDNG
     HFQLDDFSVY YSGHQELRRN GVALIAHKNI AHAVESYTIF SDRIVAICIC GKPLNVTVLQ
     VYAPTTDAPE DESERFYTKI EEALEQVPKK DIIYIMGDFN AKVGSQEEAN IIGRCGLGER
     NKAGDSLVKF CHENHFRVSN TWFMQPKHCL YTWTAPNGQH RNQIDYILCS QRWKSSVLTI
     KTFHGADCGS DHELLVTTFK VKFCNIKQEH IPYKKLEKRS KWLSAETIKV ADQRRAAKAT
     GDRDEARRLN AEFQRAARKD KEAYWDQRCK QMEEDCRKGH TRNLFAPVKK IRTYFTARKG
     AIKDKNRKVL TGQQCIRSRW REYTEELYAS TSDPETPHDI PVKMEPAILE PNNKAPSIDC
     IPEEMLRPVP PVAIKAICQK IWETSRWPKD WKRSVFIPLP KKGDARDCCN YCTIALIRHA
     SKVLLKIIEQ SLHPIIEAEL PESQAGFKRG RGTSDHITNL RWITEKCHEY QKNVYICFIY
     YSKAFDFIKH DKLWKALGYI LSPFLFNLFA EIIMRKELEI GVKIGGRNIN NLRYADDTIL
     LAETEDGLKY LILRIKKESE KMGLHLNIKK TNIMTTAGNG AVKITINSEE IKCVKVFCFL
     GSMIDRTGDC GPEISRSAML SMHQIWKSKD ISLTTKCKMV HAIVFPISMY GCESWTLKKD
     RKRMDSFELW CWRRLLWIPW TARVTNKEVL ERIKPEISLV GKVTRLQLTY VGHMMR
//