ID W5N0Q5_LEPOC Unreviewed; 576 AA.
AC W5N0Q5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Family with sequence similarity 126 member A {ECO:0000313|Ensembl:ENSLOCP00000014214.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000014214.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000014214.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- SIMILARITY: Belongs to the Hyccin family.
CC {ECO:0000256|ARBA:ARBA00034482}.
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DR EMBL; AHAT01004554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5N0Q5; -.
DR STRING; 7918.ENSLOCP00000014214; -.
DR Ensembl; ENSLOCT00000014243.1; ENSLOCP00000014214.1; ENSLOCG00000011562.1.
DR eggNOG; KOG4688; Eukaryota.
DR GeneTree; ENSGT00390000011295; -.
DR HOGENOM; CLU_027457_3_0_1; -.
DR InParanoid; W5N0Q5; -.
DR OMA; RWKRHGD; -.
DR Proteomes; UP000018468; Linkage group LG11.
DR Bgee; ENSLOCG00000011562; Expressed in camera-type eye and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IBA:GO_Central.
DR GO; GO:0072659; P:protein localization to plasma membrane; IBA:GO_Central.
DR InterPro; IPR018619; Hyccin.
DR PANTHER; PTHR31220:SF4; HYCCIN; 1.
DR PANTHER; PTHR31220; HYCCIN RELATED; 1.
DR Pfam; PF09790; Hyccin; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT REGION 359..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 576 AA; 62051 MW; 8F1243C823FA7C82 CRC64;
MLAMDQGVVE EWLSEFKTLP ETAISSYAAS LKDKTSLVPA LYKVIQEPQS ELLEPVCHQL
FEFYRSGEPR LQRFALQLLP ELLWCYLSLA GGRGPRCSGC VEALLLGIYN LEIVDKDGQS
KVLSFTVPSL SKPSVYHEPS MFGSLALTEG ALAMHGLSRV VYSGPHPQRE TFTAQNRFEV
LTFLLLCYNA ALSYMTSASL QSLCQLSSRV STCGYPRQHL RKYKGVNTRL SVSSEFLVQL
ITGIYYAMYN GESEMASKAL DDVLYRAQLE LYPEALLVGN AIKSSWHGEA LKSNKEGTRC
IQVEITPTSS RISRNAVTSL SIRGHRWKRH VPTLESPESS AEAADTAAVS VPEISVTGVS
GERVVNGDSQ RNRAEGETQG GQELGADSRA DALDLTSPED LMEISEADEG FCSRAAPSSS
PPVIVVSSSA PSGKPSGKSQ RKAGGGGGGG GRVGKDREAG SESCREQLSR KQAQRAMSEN
LELLSLKRLT LTTSQSLPKP GSLSLSHTAS AVFSKSFEQV SGVFGAGRSA GASEASRCSA
CSLQEEKLAY VSEHLSPAPP HKPRPPSISI QLSTDL
//
