ID W5N1I6_LEPOC Unreviewed; 319 AA.
AC W5N1I6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Polycomb group ring finger 6 {ECO:0000313|Ensembl:ENSLOCP00000014495.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000014495.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000014495.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01017381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5N1I6; -.
DR STRING; 7918.ENSLOCP00000014495; -.
DR Ensembl; ENSLOCT00000014524.1; ENSLOCP00000014495.1; ENSLOCG00000011792.1.
DR eggNOG; KOG2660; Eukaryota.
DR GeneTree; ENSGT00940000158034; -.
DR HOGENOM; CLU_046427_4_0_1; -.
DR InParanoid; W5N1I6; -.
DR OMA; IMCSICK; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000011792; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0035102; C:PRC1 complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd17085; RAWUL_PCGF6; 1.
DR CDD; cd16738; RING-HC_PCGF6; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046979; PCGF6_RAWUL.
DR InterPro; IPR038037; PCGF6_RING-HC.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45893; POLYCOMB GROUP RING FINGER PROTEIN; 1.
DR PANTHER; PTHR45893:SF2; POLYCOMB GROUP RING FINGER PROTEIN 6; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 98..137
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..70
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 35865 MW; 3B19D682CDAEE182 CRC64;
MEAESSEAIS SVFGVEDNGG EAKTAVEEAG ADDEIEQGSG FELDLEAGEE GLDSNENSKE
EDENEESEHG SAADEGDSSD DKDERTFPLF EVFPYIRCTL CNGYFVDATT ITECLHTFCK
SCIVKHFFYS NRCPNCNVVV HQTQPLYNIR LDRQLQDIVY KMVPHLEERE RKRMHDFYQE
RGLEVPKPAA PPPTVKTSKQ KKGLLPQSVF TIPPELDVSL LLEFVGAEEG IDNYKPLERK
YVRVSGEATV RHVELFIRRK MELNPGCQVD VVCGDHLLDR CQSLRDIQNT MGESAIQVGI
QTNAYPMPVV YAGSWLLLT
//
