ID W5N1X9_LEPOC Unreviewed; 1936 AA.
AC W5N1X9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLOCP00000014638.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000014638.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000014638.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; AHAT01000310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000014638; -.
DR Ensembl; ENSLOCT00000014667.1; ENSLOCP00000014638.1; ENSLOCG00000011877.1.
DR eggNOG; KOG0161; Eukaryota.
DR GeneTree; ENSGT00940000163461; -.
DR HOGENOM; CLU_000192_8_1_1; -.
DR InParanoid; W5N1X9; -.
DR OMA; TIQYNFR; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000011877; Expressed in embryo and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0032982; C:myosin filament; IBA:GO_Central.
DR GO; GO:0016460; C:myosin II complex; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF44; MYOSIN-13; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 33..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..780
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 657..679
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1887..1936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 181..188
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1936 AA; 222831 MW; 8408E967D15DD5A7 CRC64;
MSGDSEMSIF GEAAKYLRKS EKERLEAQSR AFDARTACFV DDDKELYVKG VIQSKEGGKV
TVKTEDNRTV TVKDNQVYPL NPPKFDKIED MAMMTHLNEP CVLYNLKERY AAWMIYTYSG
LFCVTVNPYK WLPVYNPEVV AAYRGKKRME VPPHIFALSD NAYQFMLTDA DRENQSILIT
GESGAGKTVN TKRVIQYFAS IATSGDKKKA EYTSKMKGTL EDQIIQANPL LEAFGNAKTV
RNDNSSRFGK FIRIHFAASG KLSSADIETY LLEKSRVTFQ LSSERNYHIF YQLTCNKKPE
LIEMLLISSN PYDFTYISQG EVAVKSIDDA AELMATDEAI DILGFSADEK NGIYKLTGAV
MHYGNLRFKQ KQREEQAEPD GTEVADKAAY LMGLNSSEFL KCLCYPRVKV GNEYVTKGQS
VQQVYNSVGA LGKSVYEKMF LWMVIRINQQ LDTKQARQQF IGVLDIAGFE IFDFNTLEQL
CINFTNEKLQ QFFNHHMFVL EQEEYKKEGI DWEFIDFGMD LAACIELIEK PMGIFSILEE
ECMFPKSTDT SFKNKLYDQH LGKSASFLKP KHVKGKAEAH FSLGHYAGTV DYNISGWLEK
NKDPLNESVV QLYQKSSLKL LSFLYSSYAG DDAGAKKGGK KKGSSFQTVS ALFRENLNKL
MSNLKTTHPH FVRCLIPNET KTPGAMENHL VVHQLRCNGV LEGIRICRKG FPSRIQYGDF
KQRYRVLNAS AVPEGQFMDN KKASEKLLGS IDIDHTQYKF GHTKVFFKAG LLGVLEEMRD
ERLAQLVTCI QSVCRGNLMR NEFKKMMERR ESLFTIQYNI RSFMNVKHWP WMKLYFKIKP
LLMSAEAEKE MANMKEEFAK CKEDLAKSEA RRKELEEKMV SIIQEKNDLF IQVQAEADNL
TDAEERCEGL IKSKIQLEAK LKEITERLED EEEMNAEMTA KKRKLEDECS ELKKDIDDLE
LTLAKVEKEK HATENKVKNL TEEMGSLDEN ISKLSKEKKA LQEAHQQTLD DLQVEEDKVN
TLNKAKTKLE QQVDDLEGSL EQEKKIRLDL ERAKRKLEGD LKLAQESIMD LENEKQQMEE
KLKKKDFEVT QLQGRIEDEQ VLGSQLQKKI KELQARIEEL EEEIEAERAA RAKVEKQRAD
LSRELEDISE RLEEAGGATS AQIEMNKKRE AELQKLRRDL EEATLQHEAT AAALRKKHAD
TVADLGEQID NLQRVKQKLE KEKSELKMEV DDLSSNMEAV SKSKANLEKL CHSLEDQLLE
VKVKEDENHR LISDLTAQKS RLQTENGELY RQLEERESLV SQMTRVKQAF SQQIEELKRQ
NEEDTKAKNA LAHALQSSRH DCDLLREQFE EEQEAKAELQ RSMSKANSEV AQWRTKYETD
AIQRTEELEE AKKKLAQRLQ EAEEAIEATN SKCSSLEKTK QRLQGEVEDL MMDVEKANAA
AAILDKKQRN FDKILAEWKQ KYEETQAELE SALKEVRSIG TENFKMKNAY EESLEHLETL
KRENKNLQQE ITDLTEQLGE NGKSIHELEK ARKQAEQERG EIQSALEEAE ASLEHEEGKI
LRVQLELNQV KSEIDRKIAE KDEEIEQLKR NNQRVIDTLQ STLDAEVRSR NDALRMKKKM
EGDLNEMEIQ LSHANRQASE SQKQLRNIQA QLKDAQLHLD DALRGHEDMK EQVAMVERRN
NLMQAEIEEM RAALEQTERG RKVAEQELLD SSERVQLLHS QNTSLINSKK KLESDLTQCQ
GEIEDAIQEA RNAEEKAKKA ITDAAMMAEE LKKEQDTSAH LERMKKNLEV TVKDLQHRLD
EAEQLAMKGG KKQLQKLETR VRELENELEA EQKHGADAIK GVRKYERRVK ELTYQCEEDK
KTVARLQDLV DKLQLKVKAY KRQAEEAEEQ ANSHLSKFRK VQHELEEAEE RADIAESQVN
KLRAKSRDIG AKGKED
//
