ID W5N235_LEPOC Unreviewed; 205 AA.
AC W5N235;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000014694.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000014694.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01005449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5N235; -.
DR STRING; 7918.ENSLOCP00000014694; -.
DR Ensembl; ENSLOCT00000014723.1; ENSLOCP00000014694.1; ENSLOCG00000011952.1.
DR eggNOG; KOG4047; Eukaryota.
DR GeneTree; ENSGT00940000155980; -.
DR HOGENOM; CLU_030101_1_1_1; -.
DR InParanoid; W5N235; -.
DR OMA; CDESAMS; -.
DR Proteomes; UP000018468; Linkage group LG6.
DR Bgee; ENSLOCG00000011952; Expressed in bone element and 12 other cell types or tissues.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21258:SF14; DOCKING PROTEIN 2; 1.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR Pfam; PF02174; IRS; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS51064; IRS_PTB; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 3..120
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 151..205
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
SQ SEQUENCE 205 AA; 23251 MW; 79F6517114E3459D CRC64;
MEQPAREGML YMQGAKFGMK SWKRTWVMLF QASPYGIGRV ELCDIRDGGS GGVAAAGKQG
LKKTDKKVIR LDDCVSITSA PHESCPKDSI AFYLNTTQRT YTLASEQAQE WITKLCQLAF
QKRDGDTNTV ARQESSEIPM EENELYSAWK KDQEYEVTVQ KTEASARCCL TGTYLLALDG
EAITLLDPQT KEVVYYWPYQ LLRRF
//
