ID W5N2J2_LEPOC Unreviewed; 448 AA.
AC W5N2J2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Pleckstrin homology domain containing S1 {ECO:0000313|Ensembl:ENSLOCP00000014851.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000014851.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000014851.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHAT01017305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015202901.1; XM_015347415.1.
DR AlphaFoldDB; W5N2J2; -.
DR STRING; 7918.ENSLOCP00000014851; -.
DR Ensembl; ENSLOCT00000014880.1; ENSLOCP00000014851.1; ENSLOCG00000012069.1.
DR GeneID; 107077385; -.
DR KEGG; loc:107077385; -.
DR CTD; 79949; -.
DR eggNOG; ENOG502RDEC; Eukaryota.
DR GeneTree; ENSGT00390000006729; -.
DR HOGENOM; CLU_049125_1_0_1; -.
DR InParanoid; W5N2J2; -.
DR OMA; RICVARW; -.
DR OrthoDB; 4237487at2759; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000012069; Expressed in pharyngeal gill and 6 other cell types or tissues.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR042986; PLEKHS1.
DR PANTHER; PTHR47014; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1; 1.
DR PANTHER; PTHR47014:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 24..143
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 167..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 50580 MW; 7F3EC3D71B944B4C CRC64;
MLSRVSLRNS GPRAVFYRTD DGFEDIVTGS LLKSPPTGLL KTLKSWKRRF FVLKKTSDNA
YILKYYKSDE DRSKPQGVID ISTISYIYLS PENHVKWNVI QKMFKCSPEM VLFIRSGLRD
YFLIGENKEE MDLWFESIYN ILMSLSQKEH WSPERVECLT QRTRIGSKDS FSDQGSLDEE
ELKIRSSSDP EMTKECSSIK EGESKSRSSS NPETAKGCST MTEASANSSH NVDSSPRYSD
PEVAICPSPA YYDVPRNIMK DVTERNGRDF EKTEENGPSF YMEMESVYKT AKEVQPSNTD
DAAPPCSKDK DDLGESNESL LHTINVALEG LQFQIKLLNE DQQRQTVGIT ENQIPVEKDV
YINQSDLKDS LFLTEVDGKP CISQCLGLPN SGCLFHKGDQ ILAVNDLQTQ NVKEVQTYLS
KLLKAQVKIT IQRIPGSGLL NSDTCACD
//
