ID W5N7M1_LEPOC Unreviewed; 258 AA.
AC W5N7M1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000256|ARBA:ARBA00039894};
DE EC=2.3.2.23 {ECO:0000256|ARBA:ARBA00012486};
DE AltName: Full=E2 ubiquitin-conjugating enzyme Z {ECO:0000256|ARBA:ARBA00041798};
DE AltName: Full=Ubiquitin carrier protein Z {ECO:0000256|ARBA:ARBA00042401};
DE AltName: Full=Ubiquitin-protein ligase Z {ECO:0000256|ARBA:ARBA00042316};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000016630.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000016630.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AHAT01031010; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5N7M1; -.
DR STRING; 7918.ENSLOCP00000016630; -.
DR Ensembl; ENSLOCT00000016660.1; ENSLOCP00000016630.1; ENSLOCG00000013488.1.
DR eggNOG; KOG0895; Eukaryota.
DR GeneTree; ENSGT00940000159091; -.
DR HOGENOM; CLU_1079844_0_0_1; -.
DR InParanoid; W5N7M1; -.
DR OMA; MIAHTIT; -.
DR Proteomes; UP000018468; Linkage group LG15.
DR Bgee; ENSLOCG00000013488; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR46116; (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME; 1.
DR PANTHER; PTHR46116:SF26; UBIQUITIN-CONJUGATING ENZYME E2 Z; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 147..258
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 258 AA; 26352 MW; 4B0E60C1F7E92963 CRC64;
MAESAGEEAS GIGVTGSTHS GGGAQFSPGS GNSVPGDPSG AAPDSVPSAA AAPETVPPVS
TPDIPSLPAS AIGVLGTAVG TAILAPSPGL GPAAPAMVGT AVLSPSIGLG VTGTPNLAGA
GLLSQIHSTF WDPTVSSDWD SEKPSQQCIL RIKRDIMSIY KEPPPGMFVV PDPHDMTKIH
ALITGPFDTP YEGGFFLFLF RCPPDYPIHP PRVKLITTGN NTVRFNPNFY RNGKVCLSIL
GTWTGPAWSP AQSISSVL
//
