ID W5N826_LEPOC Unreviewed; 658 AA.
AC W5N826;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Plastin-3 {ECO:0000256|ARBA:ARBA00039437};
DE AltName: Full=T-plastin {ECO:0000256|ARBA:ARBA00041485};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000016785.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000016785.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AHAT01007434; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5N826; -.
DR STRING; 7918.ENSLOCP00000016785; -.
DR Ensembl; ENSLOCT00000016815.1; ENSLOCP00000016785.1; ENSLOCG00000013613.1.
DR eggNOG; KOG0046; Eukaryota.
DR GeneTree; ENSGT00950000183097; -.
DR HOGENOM; CLU_015284_2_0_1; -.
DR InParanoid; W5N826; -.
DR OMA; TVNHLYV; -.
DR Proteomes; UP000018468; Linkage group LG7.
DR Bgee; ENSLOCG00000013613; Expressed in embryo and 13 other cell types or tissues.
DR GO; GO:0005884; C:actin filament; IBA:GO_Central.
DR GO; GO:0032432; C:actin filament bundle; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IBA:GO_Central.
DR GO; GO:0051639; P:actin filament network formation; IBA:GO_Central.
DR GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR GO; GO:0039019; P:pronephric nephron development; IEA:Ensembl.
DR GO; GO:0072114; P:pronephros morphogenesis; IEA:Ensembl.
DR CDD; cd21328; CH_PLS3_rpt2; 1.
DR CDD; cd21334; CH_PLS3_rpt4; 1.
DR CDD; cd21292; CH_PLS_rpt1; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR PANTHER; PTHR19961:SF32; PLASTIN-3; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 4.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 2.
DR PROSITE; PS50021; CH; 4.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 40..75
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 80..115
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 151..267
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 295..406
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 425..534
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 546..655
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 658 AA; 73919 MW; 0CF9A77C9411843B CRC64;
MEIVPYPAVL RAACFQKTGN SLGAEPEGSQ REMAGKISKD ELEELREAFE KVDLNGNGYI
CDYELHELFK EANLPLPGYK VREIIQRLME EGDKDKDNRI SFDEFVSIFQ ELKSSDIAKS
FRKAINRKEG ILAIGGTSEL SSEGTQHSFS EEERFAFVNW VNKALENDPD CKHVVPMDPN
SNSLFKAVGD GIVLCKMINL SVPDTIDERT INKKKLTPFT TQENLNLALN SASAIGCHVV
NIGAQDLREG KPHLVLGLLW QIIKIGLFAD IELSKNEALA ALLRDGETLE DLMKLSPEEL
LLRWANFHLE NAGWNKINNF SSDIKDSRAY FHLLNQIAPK GTKEGETRID INMSGFNEKD
DLKRAELMLQ EAEKLGCRQF VTPSDVVSGN PKLNLAFVAN LFNKYPALIK PENQDIDWGL
LEGETREERT FRNWMNSLGV NPHVNHLFAD LQDALVILQL YENIKVRVDW NRVNKPPYPK
IGTNMKKLEN CNYAVDLGKK DAKFSLVGIG GQDLNDGNPT LTLAVVWQLM RRYTLNVLEH
LGDGEKATDE IIVKWVNKAL SEAGKKTKIQ SFKDKEISSS LPVLDLIDAI QPSSINYDLV
KTGSLSEEDK LENAKYAISM ARKIGARVYA LPEDLVEVKP KMVMTVFACL MGRGMKKV
//
