ID W5N9I6_LEPOC Unreviewed; 1330 AA.
AC W5N9I6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Nucleoporin 210 {ECO:0000313|Ensembl:ENSLOCP00000017295.1};
GN Name=NUP210 {ECO:0000313|Ensembl:ENSLOCP00000017295.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000017295.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000017295.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NUP210 family.
CC {ECO:0000256|ARBA:ARBA00007313}.
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DR EMBL; AHAT01015109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000017295; -.
DR Ensembl; ENSLOCT00000017326.1; ENSLOCP00000017295.1; ENSLOCG00000014031.1.
DR eggNOG; KOG1833; Eukaryota.
DR GeneTree; ENSGT00390000009491; -.
DR HOGENOM; CLU_001205_1_0_1; -.
DR InParanoid; W5N9I6; -.
DR OMA; YLCLVTM; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000014031; Expressed in embryo and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:Ensembl.
DR GO; GO:0048628; P:myoblast maturation; IEA:Ensembl.
DR Gene3D; 2.60.40.1080; -; 1.
DR InterPro; IPR003343; Big_2.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR InterPro; IPR045197; NUP210-like.
DR PANTHER; PTHR23019:SF2; NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210; 1.
DR PANTHER; PTHR23019; NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; 1.
DR Pfam; PF02368; Big_2; 1.
DR SMART; SM00635; BID_2; 2.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 2.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 479..545
FT /note="BIG2"
FT /evidence="ECO:0000259|SMART:SM00635"
FT DOMAIN 1105..1180
FT /note="BIG2"
FT /evidence="ECO:0000259|SMART:SM00635"
SQ SEQUENCE 1330 AA; 146048 MW; 11FD79F02950D497 CRC64;
MYKDHIAPRG PLTLCFYLKQ KSTLEKKKEM ASATVLSLIV LMVLFYDPIF CSSASKLNIP
KVLLPLARST KINFTLEATE GCYRWSSTRP EVASIDAVDL DERQCSQRAI LQARSSQLTR
LTSIIIAEDV LTGQVLRCDA IVDVISEIQI VSTTRELHLE DSPLELRIHA LDSEGNTFST
LAGLVFDWSI VKDADTASFS DSYNALRVLK FSESTYTPPA YISEMEKVGK QGDIILVSGI
KTGNSKIKAK IQESLYKNVP AAEVRLLILE NILLNPAYDI YLLVGTSIQY RVQKIRQGKI
TELVMPCDQY ELQLQNSILG PDGDVRIPVA KLDRATSTVT ALQRGQTNIV LDHKSLRMQG
ASRLPNSTLY VVEPGYLGFK IHPGDRWVLE TGRTYEILIE VFDKSSNKVH LSDNIRIEAV
FPKAYFKILE SSFNGSYHHV KALQNGQTVI DAALTSVVDQ DGGVHVFSIP VRNQQDVEIY
NPIVLTPRIL TFPWQPKIGA YQYTIKADGG SGNFTWSSSN QDVATVTVKG VMTTVSDVGV
SVVQAHDVQN PLHYGKMKVY VIEPVGMDFI PCQVEARVGQ TLDLPLRIFG LLSVETGEKV
TLSDCSHFDL VVEVENKGIF KFLEGRLKPG QDYCSGVRVQ ALATGDTVLL VSYTHGHLHL
SARITIAAYQ PLKAIDPVSV ALVTLGSSKD MLFEGGPKPW VLEPSKFFRN LTAEDPGSVG
LALFGPASRN YFQHWVRATC RAFGEQVLAV TVGNQPSLTN PFPAVEPAVV KLVCAPPSRL
TLVPVYTNPQ LDLSCPLLQQ NKQLVPVSNY RNPVLDLAVY DQQGRKFDNF SSLSIIWEST
KVSLASIEPT MPMEQHIKED GNGQKKLHGR QTVLVHRESG VTAITVTAIG YQASHLSAAR
VQSLYDPLTA VSATLELLLV KDVQVSPEAI TIYNHPDVRA ELALREGSGY FFVNTSIGGI
ANIAYQESRG TAEVLPIRPG ILQAMVHDLC LAFPAPAKAS IHISDIFEVY VRVVDKVEIG
KSVKAYVRVL DDNKKPFLAK YFHFMDLKLK AASPIVSLLP LSESSENDTA TFLVQGLTIG
QTSLAAVVLD KSGKRISSAP QQIEVFPPFR LIPRKVTLII GGMMQITSEG GPQPQSHIIF
SIGNEKIASV NSNGLTRGIT VGNVTVTGVV QAVDAETGKL VIVSQDQVHV EVLQLKAVRI
RAPITRMKTG TQMPVYVMGI TSSQTPFSFG NALPGLTFHW SVTKRDILDI QTRHSEASLQ
LPAENNFAMN VYGRTKGRTG LKVVVKTVSP ASGHLEGNVP ELSDEIQIQV LTCSFYFGVE
CLILHSIVKY
//
