ID W5NAE1_LEPOC Unreviewed; 490 AA.
AC W5NAE1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLOCP00000017600.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000017600.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000017600.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; AHAT01040429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NAE1; -.
DR STRING; 7918.ENSLOCP00000017600; -.
DR Ensembl; ENSLOCT00000017632.1; ENSLOCP00000017600.1; ENSLOCG00000014296.1.
DR eggNOG; ENOG502QSRZ; Eukaryota.
DR GeneTree; ENSGT01070000253822; -.
DR HOGENOM; CLU_013137_22_2_1; -.
DR InParanoid; W5NAE1; -.
DR OMA; WARKERN; -.
DR Proteomes; UP000018468; Linkage group LG1.
DR Bgee; ENSLOCG00000014296; Expressed in intestine and 5 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0005102; F:signaling receptor binding; IBA:GO_Central.
DR GO; GO:0001817; P:regulation of cytokine production; IBA:GO_Central.
DR GO; GO:0050852; P:T cell receptor signaling pathway; IBA:GO_Central.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 245..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..141
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 155..233
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 316..490
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 490 AA; 55277 MW; DB00856D2ECC2539 CRC64;
LTGTDMLCTL GRSLSVIVAL LQVRGASPGS FTVQVPDKPL VAQLGADLML PCHLSPAHSA
EPLEVRWARK ERNEEVHLYR HRTEKQGRAF EGRVSLFKDS LKQGNVSLLI RDLQVSDEGL
YTCFVDSGSY YDRGEVEVKI SMTGSAPLVS LEGHEGGGIR LSCHSEGWYP APEVLWADET
GAPVPKTRGI FTRSREGLYS VSTHLLLSGQ GQAEVSCVLE FGGNGRQIQS RIHVSGAFFT
PAQPWFISAV VLVVIFLISL TSLADGRWGD MERILLLSRQ TLDKHCFCLC SCTGAEEGQW
VSLDRRHTAW CPYMVKLNYT TVCVEIKEGG FQKADIIMDK ETSHPKLRVS EDGKRVQYDE
SLNDVPNNER RYKYWSGVLG TQGFSNGKHY WEVNVGELDH WDLGVAYETV RKDLIGDIQP
NHDYMSIWFV YNEYRALDTT RPRIQTKGTV HTVGVFLDYE GGKVSFYDVE NKFHLYTFSK
NFERTLYPFF
//
