ID W5NDM9_LEPOC Unreviewed; 616 AA.
AC W5NDM9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like 2 {ECO:0000313|Ensembl:ENSLOCP00000018738.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000018738.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000018738.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01025444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01025445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01025446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NDM9; -.
DR Ensembl; ENSLOCT00000018770.1; ENSLOCP00000018738.1; ENSLOCG00000015224.1.
DR GeneTree; ENSGT00940000160423; -.
DR HOGENOM; CLU_011864_2_2_1; -.
DR Proteomes; UP000018468; Linkage group LG8.
DR Bgee; ENSLOCG00000015224; Expressed in ovary and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11469; bHLH-PAS_ARNTL2_PASD9; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR23042:SF48; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 89..142
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 161..225
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 360..409
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..480
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 67762 MW; 9D8B07F098C45E16 CRC64;
MSAAGGDDRA AGEQTEDVLA EESQGLSVPL SSLMPPAPAT GVSSGSPVSS MDLPRKRKGS
TDNLDPVDVD MEDEQDRAEG DDLQVKVKCF REPHSQIEKR RRDKMNNLID ELSAMIPPCN
PVSRKLDKLT VLRMAVQHLK SLKGATSSFA EASYKPSFLP DDELKHLVLR AADGFLFVVG
CDRGKILFVS ESVSKILNYS RAELIGQSLF DYVHPKDIAK VKEQLSASEV FPRERLIDAK
TGLQVQTDIP VGTARLCSGA RRSFFCRMKY NRVVVKTEDK DFKPSTSKKK EFQRYCTVHC
TGYMRSWPAS QVGVESDSEK ASNNFSCLVA IGRLHPHTLP PANGEVKVKP TEFVMRCAVD
GKFTFVDQRA TTVLGYLPQE LLGTSCYEYF HQDDLVHLAD RHRKVLRSKE KIETNCYKFK
TKYGSFVTLQ SQWFSFVNPW TKEVEYIVST NTVISGAHSS PRDSDDKLEQ PSDSKSTEEV
SKKSFPIIPG ISSGPGTMIY AGSIGTQIAN ELLDFNRLNS SPSSGNASPF SLLQDKSPLA
VPPASNVPNG EVVDSEVPHK PSQEGDSAQL DLDMVVGPGL GSLSNDEAAM AVIMSLLETE
GNLGEAVDFN EMHWSL
//
