ID W5NDS9_LEPOC Unreviewed; 429 AA.
AC W5NDS9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000018788.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000018788.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc
CC subfamily. {ECO:0000256|ARBA:ARBA00005530}.
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DR EMBL; AHAT01025405; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NDS9; -.
DR STRING; 7918.ENSLOCP00000018788; -.
DR Ensembl; ENSLOCT00000018820.1; ENSLOCP00000018788.1; ENSLOCG00000015269.1.
DR eggNOG; ENOG502RGC5; Eukaryota.
DR GeneTree; ENSGT00940000164185; -.
DR HOGENOM; CLU_028381_3_2_1; -.
DR InParanoid; W5NDS9; -.
DR OMA; TCKDMVA; -.
DR Proteomes; UP000018468; Linkage group LG8.
DR Bgee; ENSLOCG00000015269; Expressed in mesonephros and 3 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0045130; F:keratan sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0001517; F:N-acetylglucosamine 6-O-sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0042339; P:keratan sulfate metabolic process; IBA:GO_Central.
DR GO; GO:0006044; P:N-acetylglucosamine metabolic process; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016469; Carbohydrate_sulfotransferase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10704; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10704:SF66; SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PIRSF; PIRSF005883; Carbohydrate_sulfotransferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022968}.
FT DOMAIN 79..400
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 429 AA; 49283 MW; 9F47551E238FF4C2 CRC64;
DVDCREAGGM ECSWKTVVLL VCASLGIQYT AIRSLRASLP SPCPGGDLCP HRDLKEYGWR
SLCDDGIQPP GTSHFHGRNH IILFATTRSG SSFTGQLFNQ HPDIFYLFEP LYHVQQAFTN
SSTRLRKILD RRALLGAYRD LLHNLYNCDF YFLENYIKPE PRDHVTGSFF RRSSSSALCS
HPVCKELPDT EEPDEIWCSK KCRTLNLTLA ARACQKRGSM AIKTVRIPEI KDLKILSEDP
RLNLKIVHLV RDPRGILASR MVAFMDQFRA WKIWNATGRR PHYIDLSQIT RTCQDLSDSA
ETGFQKPSWL RGKYLLVRYE DLAKNPEEKA KEIYKFIGLE MDEKVRTWIM HNTNRSAIPE
GNYKFSTTRN SKATAESWRL NLAFDIVQTV QTVCNNTLYL LGYKPVNSVT DLRNMSNSLV
EPRNFLPFL
//
