ID W5NEU2_LEPOC Unreviewed; 478 AA.
AC W5NEU2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Zinc-binding protein A33-like {ECO:0000313|Ensembl:ENSLOCP00000019151.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000019151.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000019151.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01031379; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015198683.1; XM_015343197.1.
DR AlphaFoldDB; W5NEU2; -.
DR STRING; 7918.ENSLOCP00000019151; -.
DR Ensembl; ENSLOCT00000019183.1; ENSLOCP00000019151.1; ENSLOCG00000015558.1.
DR GeneID; 102688424; -.
DR KEGG; loc:102688424; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000154126; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR InParanoid; W5NEU2; -.
DR OMA; SHESPIC; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000018468; Linkage group LG1.
DR Bgee; ENSLOCG00000015558; Expressed in bone element and 10 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR CDD; cd19772; Bbox2_TRIM21_C-IV; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF639; E3 UBIQUITIN-PROTEIN LIGASE TRIM39; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 17..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 93..134
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 282..478
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 181..241
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 478 AA; 54546 MW; 03B2E91E7F0018BC CRC64;
MDCSEDQMEK LRRDLSCPVC SDLLKAPVLL ECGHHFCREC IRSRWEGPEE SARCPLCGRT
AAHKVAQDAP LLGSIVGRVR ELAAKRDAAA KRKRESYCAL HDERLELFCQ EDGEAICFVC
ACSQRHRSHA KTALDCALRQ YTEKAQALWQ LLQTELKEAV QCQCDTEQRI ASLQEDQRLI
REKMDAEFAQ IRRLLDQEEE ALRARLREDE ELKRSELERS RVQAQQEVMR LEEAARDVQG
KRALCDSPAA VKEVKALLNR NDWTFKKPLN SSLGLLAEEH VGPLQYKVWM RVKELISPGL
HPVTLDPDTA HPCLLLSDGN TSVRSAGVKT DVPAHPDRCE HYLDVLGSQG FDSGRHYWEV
WVDGKTQWEL GVIGASVDRK GLYKTALPRK VWTLRWNSGS YEACNQTVVQ LCVKTRLCKV
GVYLDYDEGK LVFYNAEGMT LLYAFSNHFQ ETIYPLFNPG FTEHLETTKP LKIINPQF
//
