ID W5NEU5_LEPOC Unreviewed; 922 AA.
AC W5NEU5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Transportin 3 {ECO:0000313|Ensembl:ENSLOCP00000019154.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000019154.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000019154.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AHAT01029084; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006633284.1; XM_006633221.2.
DR AlphaFoldDB; W5NEU5; -.
DR STRING; 7918.ENSLOCP00000019154; -.
DR Ensembl; ENSLOCT00000019186.1; ENSLOCP00000019154.1; ENSLOCG00000015556.1.
DR GeneID; 102691611; -.
DR KEGG; loc:102691611; -.
DR CTD; 23534; -.
DR eggNOG; KOG2081; Eukaryota.
DR GeneTree; ENSGT00530000063347; -.
DR HOGENOM; CLU_005996_0_2_1; -.
DR InParanoid; W5NEU5; -.
DR OMA; LECITSW; -.
DR OrthoDB; 5343383at2759; -.
DR Proteomes; UP000018468; Linkage group LG8.
DR Bgee; ENSLOCG00000015556; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:Ensembl.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR GO; GO:0008380; P:RNA splicing; IEA:Ensembl.
DR GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR PANTHER; PTHR12363; TRANSPORTIN 3 AND IMPORTIN 13; 1.
DR PANTHER; PTHR12363:SF33; TRANSPORTIN-3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 32..94
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03810"
FT DOMAIN 102..248
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
SQ SEQUENCE 922 AA; 104109 MW; 209CE79846D4B2FA CRC64;
MEGGKPSLSL VYQAVQALYH DPDPAGKERA SVWLGELQRS MYAWEISDQL LQIKQDVESC
YFAAQTMKMK IQTSFYELPA ETHISLRDSL LSHIQNLKDL SPIIVTQLAL AIADLALQMA
SWKGCVQTLI EKYSNDVSSL IFLIEILTVL PEEVHSRSLR IGANRRTEII EDLAYYSSTV
VTLLMSCVEK TGSDEKMLIK VFRCLGSWFN LGVLDSNFMA NNQLLMILFQ VLQRDETSTN
LHEAASDCVC SALYAIENVD NNMPLALQLF QGVLTLETAY HMAVAREDLD KVLNYCRIFT
ELCETFLETI VRSPGQGLGD LRTLELLLIC AGHPQYEVVE ISFNFWYRLG EHLYKSDPVL
HAIFRPYIQR LLHALARHCQ LDPDHEGIPE DTDDFGEFRM RVSDLVKDVI FLVGSMECFS
QLYATLKDGN PPWEVTEAVL FIMAAIAKSV DPENNPTLTE MLEQVVLLPQ TVHSAVRYTS
IELVGEMSEV VDRNPRFLDP VLNYLMKGLR EKPLASVAAK AIHNICSVCR DHMAQHFQGL
LDIARALDSF ALSPEAAIGL LKGTALVLAR LPLEKIAESL SDLCAVQVVA LKKLLSQEPR
NGKSSDPTVW LDRLAVIFRH TNPIVENGQT HPCQKVIQEI WPVLSETLNK HQADNRIVER
CCRCLRFAVR CVGKGSAALL QPLVTQMVNV YQIYPHSCFL YLGSILVDEY GMEEGCRQGL
LDMLQALCMP TFQLLEQPSG LRNHPDTVDD LFRLATRFIQ RSPVTLLGSQ IIIHIIQCAI
AATTLDHRDA NCSVMKFVRD LIHTGLTNDH EDDFELRKQL IQQAMNQHGQ QLVSQLIHAC
CFCLPPYTLP DVAEVIWEIM LFDRPTFCRW LESALKGLPK ETSGGAVTVT HKQLTDFHKQ
VTSAEECKQV CWALREFTRL FR
//
