ID W5NFS8_LEPOC Unreviewed; 411 AA.
AC W5NFS8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000019487.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000019487.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
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DR EMBL; AHAT01008319; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01008320; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NFS8; -.
DR STRING; 7918.ENSLOCP00000019487; -.
DR Ensembl; ENSLOCT00000019519.1; ENSLOCP00000019487.1; ENSLOCG00000015830.1.
DR eggNOG; KOG4790; Eukaryota.
DR GeneTree; ENSGT01070000253766; -.
DR HOGENOM; CLU_028534_0_0_1; -.
DR InParanoid; W5NFS8; -.
DR OMA; CGCFYLQ; -.
DR Proteomes; UP000018468; Linkage group LG1.
DR Bgee; ENSLOCG00000015830; Expressed in larva.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:1902742; P:apoptotic process involved in development; IBA:GO_Central.
DR GO; GO:0043652; P:engulfment of apoptotic cell; IBA:GO_Central.
DR GO; GO:0070782; P:phosphatidylserine exposure on apoptotic cell surface; IBA:GO_Central.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR PANTHER; PTHR16024:SF9; XK-RELATED PROTEIN 6; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 86..105
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 183..200
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 212..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 241..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT REGION 295..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 47573 MW; BC8E981E301FF581 CRC64;
CIIVIWKWKG GVSILLYTHV YRYIRTMYLG IQSRRQKEHQ RRFYWAMMYE YADVNMLRLL
ETFLESAPQL VLQLCIMIQK NRAETLQCVS SVASLLSLAW VLASYHKLLR DSRDDKKSMS
YRGALIHIFW RLFTISSRVL SFALFASIFQ LYFGIFVVVH WCAMAFWIIH GGTDFCMSKW
EEVLFNMVVG IVYIFCWFNV KEGRTRYRMV AYYAVVLTEN ALLTILWYFY RDPATTDSYA
VPALCGVFLS FASGVVCIFL YYGVLHPMGP RVRILASSCC AELLWGLPLP PEAEPMAPTP
GPRGSQATPT RGSTGDQQQE QEDLTADTCL PVFQVRPTVP TTPMGRPYHP EGPLIKIDMP
RKRYPAWDAH FVDRRLRRTI NILQYITPTA VGIRYRDGPL LYELLQYESS L
//
