ID W5NFV0_LEPOC Unreviewed; 352 AA.
AC W5NFV0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Zinc finger protein 512 {ECO:0000256|ARBA:ARBA00039955};
GN Name=ZNF512 {ECO:0000313|Ensembl:ENSLOCP00000019509.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000019509.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000019509.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR EMBL; AHAT01008358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01008359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NFV0; -.
DR STRING; 7918.ENSLOCP00000019509; -.
DR Ensembl; ENSLOCT00000019541.1; ENSLOCP00000019509.1; ENSLOCG00000015845.1.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000158595; -.
DR HOGENOM; CLU_020005_0_0_1; -.
DR InParanoid; W5NFV0; -.
DR OMA; SVEEQWY; -.
DR Proteomes; UP000018468; Linkage group LG1.
DR Bgee; ENSLOCG00000015845; Expressed in brain and 11 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR InterPro; IPR048408; ZNF512_C2HC.
DR InterPro; IPR048403; ZNF512_znf-C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR22979:SF2; ZINC FINGER PROTEIN 512; 1.
DR PANTHER; PTHR22979; ZINC FINGER PROTEIN-RELATED; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR Pfam; PF21276; ZNF512_C2H2; 2.
DR Pfam; PF21367; ZNF512_zf-C2H2; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 45..73
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 135..158
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 288..316
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 156..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 40128 MW; 81230F0ED9B6E52F CRC64;
GSQEERWHLQ ILDKGRVTCP KCKAVVRKTV EGLKKHMGNC KLNTFTCQHC GKQLKSLTGM
KYHVMADHNN LPTPEDSNGL DSHALKDRLR KVLKRMGKLK CTKEGCTGSF TSIMGYLYHT
RKCGKEESEL EKLVLNCKHC GKPYKSKAGL EYHLKSEHGP TTLKSEEEDT TMQKEADVER
TASGRVKRQS AQVAVFHLQE IAMEELLKEW PKRKVQQDLV PDDRKLKYAR PGLPAFSQDV
LKKWKNEVKM HRKVHCPNQG CDSVYTSVSG LKAHLGLCSR GDFEAGKYKC LICDKEFSSE
SGVKYHINSI HAQDWFVVSS KTTKSLEKLP KTNPKDKKAE AHKHDKWILK RP
//
