ID W5NGB6_LEPOC Unreviewed; 784 AA.
AC W5NGB6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) {ECO:0000313|Ensembl:ENSLOCP00000019675.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000019675.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000019675.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
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DR EMBL; AHAT01001623; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NGB6; -.
DR STRING; 7918.ENSLOCP00000019675; -.
DR Ensembl; ENSLOCT00000019707.1; ENSLOCP00000019675.1; ENSLOCG00000015979.1.
DR eggNOG; KOG2318; Eukaryota.
DR GeneTree; ENSGT00390000004881; -.
DR HOGENOM; CLU_010564_2_0_1; -.
DR InParanoid; W5NGB6; -.
DR OMA; YEMEMSW; -.
DR Proteomes; UP000018468; Linkage group LG16.
DR Bgee; ENSLOCG00000015979; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 692..719
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..210
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 784 AA; 91051 MW; 0464642B33FB12E3 CRC64;
MASKNSERSD ERFSRMKQDP RFWEMPETEQ KIKIDKRFQS MFHDKRFKLK YTVDKRGRPI
NHSSAEDLKR FYKVSDSEES DHEEKKAAQK MKKKKQKLRA KVDVEVGEKH LQKGKGEESS
VPEQPTKKSK ARVTVSDPEK SDLYFLRKSY LVNEEKTKFD TDDEDDDSGA DMSEVEQEEE
EGSSEEEEED DSDEGKSAED SEDESEEESD SGPDLARGKG NIETSSDEDE EDDLTDLFQP
EEELEHDWGE LWKDAPRGDN VTRRLAVCNM DWDRLKAKDL LALFNSFKPK GGVVLSVKIY
PSEFGKERMK AEQLQGPLEL VILPENPDKD TEEERLYREK MREYQFKRMR YFYAVVECDS
PETAAKIYEE CDGFEYESSC SVVDLRFIPD DITFDEQPKD VASDVDLASY TPKYFSSTAV
ATSKVELTWD ETDHERVTML NRKFKKDEIM DMDFQAYLAS SSEEESDHEG KTVAAVSVSI
KDADDEEKRA KKAPKDDAEQ IAKYRDLLKS IQDKDGKHQE KDMEMEISWV PGLKETAEQL
VKRKLEGKDK LTPWEEYLEK KKEKKKQKKM EGTKAAVGSD LSDDDLPPDV DLDDPYFAEE
LGKGGTALKN KSKAKKNKKS REEERTPEEE AELEKQRAEM ALLMDDDEDE NRKHFNYDKI
VEQQNLSKKK KKKLLKKNEL LEEDNFEVDV QDPRFQAMYT SHLFNLDPSE PAFRKTKATQ
SIVEEKRRRR EEAAQRKERE LEQESPSKLK AGSKTTMDAG LSMLVRSIKS KTEQFQARKK
QKTK
//
