ID W5NH88_LEPOC Unreviewed; 468 AA.
AC W5NH88;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Octopamine receptor 2-like {ECO:0000313|Ensembl:ENSLOCP00000019997.1};
GN Name=TARBP1 {ECO:0000313|Ensembl:ENSLOCP00000019997.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000019997.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000019997.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; AHAT01001667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NH88; -.
DR Ensembl; ENSLOCT00000020030.1; ENSLOCP00000019997.1; ENSLOCG00000016214.1.
DR GeneTree; ENSGT00390000003939; -.
DR HOGENOM; CLU_009579_3_3_1; -.
DR OMA; GWGHFEY; -.
DR Proteomes; UP000018468; Linkage group LG16.
DR Bgee; ENSLOCG00000016214; Expressed in testis and 13 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR22752:SF14; 5-HYDROXYTRYPTAMINE RECEPTOR 1B; 1.
DR PANTHER; PTHR22752; G PROTEIN-COUPLED RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..332
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 427..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 52142 MW; 87A4EA3DD31D4A22 CRC64;
LAGCRGPARF VWGARAQVRS CSSEVRLNIS ARTRLLLEVL IVLMALGAVA GNILVIVIVA
ATKTFHSVTS VLIINLAISD FLVGIGVMPF VAISVMYDGW VDCTDLCLYV GYTSSVYCTA
SVLTLAAIAL DRYYAIIDCL HYSSQSTVWR TVAAVIWIWL QAAVTSCPPL LGWSHLDYIA
PMYSCAVDWS RSPSYTGFVA AFSFMLPACI MVFCYVKIVK VARGHARRIH DLEDHLQRNR
PHPAEQEEKP TFSRLIYCIS GHGFHSKEHH GVFRLFLVIF AFFCCWMPYI IVALVQAIET
ATSHQSTHIP NNVITFAYWL ALLNSDINPL LYALLSKRFQ KALKSLRHKL HARVSQQVCN
PQTCTEHSPQ CPRNTAASSI NSVCPERAFN SSLFSLDSCT PEGYKKEQLE RTKECVCVKP
EGQGLDTQHL QVPSAPVESD KPSRPSSPSD RQVTFFYGKI TVKVEHDV
//
