ID W5NIP7_LEPOC Unreviewed; 162 AA.
AC W5NIP7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Sorting nexin-3 {ECO:0000256|ARBA:ARBA00020436};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000020506.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000020506.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, phagosome
CC {ECO:0000256|ARBA:ARBA00004262}. Early endosome
CC {ECO:0000256|ARBA:ARBA00004412}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; AHAT01009264; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01009265; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01009266; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006626028.1; XM_006625965.2.
DR AlphaFoldDB; W5NIP7; -.
DR Ensembl; ENSLOCT00000020541.1; ENSLOCP00000020506.1; ENSLOCG00000016603.1.
DR GeneID; 102688836; -.
DR KEGG; loc:102688836; -.
DR CTD; 8724; -.
DR GeneTree; ENSGT00940000153609; -.
DR HOGENOM; CLU_057172_2_2_1; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000018468; Linkage group LG1.
DR Bgee; ENSLOCG00000016603; Expressed in pharyngeal gill and 13 other cell types or tissues.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:1901981; F:phosphatidylinositol phosphate binding; IEA:InterPro.
DR CDD; cd07293; PX_SNX3; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR042137; PX_SNX3_Vert.
DR PANTHER; PTHR45963; RE52028P; 1.
DR PANTHER; PTHR45963:SF1; SORTING NEXIN-3; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 27..151
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 162 AA; 18821 MW; 34960528DF4585F5 CRC64;
MAEAIADTRR LLSKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRLKTNLPIF
KLKESRVRRR YSDFEWLRNE LERESKVVVP PLPGKALFRQ LPFRGDDGIF DDSFIEERRQ
GLEQFLNKVA GHPLAQNERC LHMFLQDETV DKNYTPSKIR QA
//
