ID W5NJ36_LEPOC Unreviewed; 389 AA.
AC W5NJ36;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1 {ECO:0000256|ARBA:ARBA00022083};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000020645.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000020645.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00025804}.
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DR EMBL; AHAT01001746; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NJ36; -.
DR STRING; 7918.ENSLOCP00000020645; -.
DR Ensembl; ENSLOCT00000020681.1; ENSLOCP00000020645.1; ENSLOCG00000016710.1.
DR eggNOG; KOG1521; Eukaryota.
DR GeneTree; ENSGT00950000183100; -.
DR HOGENOM; CLU_038421_0_1_1; -.
DR InParanoid; W5NJ36; -.
DR OMA; AQPRKCT; -.
DR Proteomes; UP000018468; Linkage group LG16.
DR Bgee; ENSLOCG00000016710; Expressed in bone element and 13 other cell types or tissues.
DR GO; GO:0005736; C:RNA polymerase I complex; IBA:GO_Central.
DR GO; GO:0005666; C:RNA polymerase III complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0001054; F:RNA polymerase I activity; IEA:InterPro.
DR GO; GO:0001056; F:RNA polymerase III activity; IEA:InterPro.
DR CDD; cd07032; RNAP_I_II_AC40; 1.
DR Gene3D; 2.170.120.12; DNA-directed RNA polymerase, insert domain; 1.
DR Gene3D; 3.30.1360.10; RNA polymerase, RBP11-like subunit; 1.
DR HAMAP; MF_00320; RNApol_arch_Rpo3; 1.
DR InterPro; IPR001514; DNA-dir_RNA_pol_30-40kDasu_CS.
DR InterPro; IPR011262; DNA-dir_RNA_pol_insert.
DR InterPro; IPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3.
DR InterPro; IPR036603; RBP11-like.
DR InterPro; IPR022842; RNAP_Rpo3/Rpb3/RPAC1.
DR InterPro; IPR033901; RNAPI/III_AC40.
DR InterPro; IPR036643; RNApol_insert_sf.
DR PANTHER; PTHR11800; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR11800:SF13; DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1; 1.
DR Pfam; PF01000; RNA_pol_A_bac; 1.
DR Pfam; PF01193; RNA_pol_L; 1.
DR SMART; SM00662; RPOLD; 1.
DR SUPFAM; SSF56553; Insert subdomain of RNA polymerase alpha subunit; 1.
DR SUPFAM; SSF55257; RBP11-like subunits of RNA polymerase; 1.
DR PROSITE; PS00446; RNA_POL_D_30KD; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 128..387
FT /note="DNA-directed RNA polymerase RpoA/D/Rpb3-type"
FT /evidence="ECO:0000259|SMART:SM00662"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..39
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 389 AA; 44072 MW; E008029A07440AD5 CRC64;
MLRLNMLAQR QEKSRSARPP ARRRCSLSAT RKHTQAWRRG ARGTSRETRT SMSGNDVEEQ
ENQQCAEMAA PRSNVEEIRD RVILGEFGVR NVHTTDFPGN YPGYDDTWNR KKFEEKFRID
VIRMDENTLE FDMVGIDAAI ANAFRRILLA EVPTMAIEKV FVYNNTSIVQ DEILAHRLGL
IPIKADPRLF EYRNAGDEEG TDIDTIQLQL KIKCTRNPRA SKDSSDPSEL YINHMVYSRD
IKWTPLGNQA DLFAEAGISP VHGDILIAQL RPGQELDIVM HCVKGVGKDH AKFSPVATAS
YRLLPEITLL QPVEGELAEK LKRCFSPGVI EIESDGGKKF AKVANSRLDT CSREVFRHDD
LKNIVKLGRV RNHFIFSVES TGILSHVIL
//
