ID W5NKP6_LEPOC Unreviewed; 737 AA.
AC W5NKP6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Zinc finger and BTB domain containing 24 {ECO:0000313|Ensembl:ENSLOCP00000021205.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000021205.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000021205.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01026735; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015211853.1; XM_015356367.1.
DR RefSeq; XP_015211861.1; XM_015356375.1.
DR AlphaFoldDB; W5NKP6; -.
DR STRING; 7918.ENSLOCP00000021205; -.
DR Ensembl; ENSLOCT00000021241.1; ENSLOCP00000021205.1; ENSLOCG00000017157.1.
DR GeneID; 102695442; -.
DR KEGG; loc:102695442; -.
DR CTD; 9841; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000159373; -.
DR HOGENOM; CLU_024445_0_0_1; -.
DR InParanoid; W5NKP6; -.
DR OMA; EQISNHH; -.
DR OrthoDB; 5350085at2759; -.
DR Proteomes; UP000018468; Linkage group LG1.
DR Bgee; ENSLOCG00000017157; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR19818:SF168; GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED; 1.
DR PANTHER; PTHR19818; ZINC FINGER PROTEIN ZIC AND GLI; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 7.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 38..104
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 280..307
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 308..335
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 336..363
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 364..391
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 392..419
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 420..447
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 448..475
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 476..503
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 130..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 82658 MW; E1264A1CCD61A5B5 CRC64;
MSESLQNPPT SIFVLSSKAY KETILNRFEE LRKKDLLCDI TLIVEDVQFK AHKALLAASS
EYFSHMFTAE GQVGQSVYML DGMAAGSFRA VLEFIYTGHV SVEENTREQL LAMAQFLKVT
DLAKAHTECQ HSRLASEENK GDSHAGQNTE EPTKPKRKRG RPRKTEVIAD VSAVASPDSS
KATESTGLGA QMTDRTAAPQ VSAEVMEGEE TADSDVHVDL SNDTDVDYDP KKEKLQHSRY
SKRKIKPPLK LNGFRLGEEV SDQGQTGKRG RKRKYPNTEA RCEQCGKVFK NHLFLTIHQR
THTGEKPYRC FECGKSFTQK HSLLVHQRMH TGERPYICTV CSKALSTKHS LLEHMSLHTE
QKLFSCDQCG RTFSQKRQLK SHYRLHTGKP LPECAQCNRR FMDAAQLKKH LRTHTGEKPF
TCEICGKCFT AKSTLQTHIR IHRGEKPYVC SVCSKSFSDP SARRRHVASH TGKKPFTCSF
CSLSFARLDN LKAHTKTHNK ERPTDAPRQV TSSESDMGVE EVRSILQLQQ YQLPTSGEQE
IQLVVTGEVD NINFVPGQEQ GISIITADDT ENLTPEQASG LTLLTQPSPH VQNLALVTQG
EQPEQIQAIS VMESQVTSGQ PEQMHVITLT KEAMEHLQAH HGTPQQVHIT QRSTQPLHLL
REPTQQIPLT QEPQAQQLQI SREQQGQAIH ISSQTTQPIS ISQPTQQIPS HQIQGQTFQI
QAGTVSYLYT TSITPQT
//
