ID W5NMK8_LEPOC Unreviewed; 292 AA.
AC W5NMK8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=MARVEL domain-containing protein {ECO:0000259|PROSITE:PS51225};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000021867.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000021867.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MAL family. {ECO:0000256|ARBA:ARBA00034721}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHAT01000519; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NMK8; -.
DR Ensembl; ENSLOCT00000021905.1; ENSLOCP00000021867.1; ENSLOCG00000017763.1.
DR eggNOG; KOG4788; Eukaryota.
DR GeneTree; ENSGT00950000182933; -.
DR HOGENOM; CLU_068368_0_0_1; -.
DR InParanoid; W5NMK8; -.
DR OMA; CLLPFDR; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000017763; Expressed in bone element and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR047123; MYADM-like.
DR PANTHER; PTHR17068:SF3; MYELOID-ASSOCIATED DIFFERENTIATION MARKER; 1.
DR PANTHER; PTHR17068; MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER; 1.
DR Pfam; PF01284; MARVEL; 2.
DR PROSITE; PS51225; MARVEL; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..146
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT DOMAIN 151..290
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
SQ SEQUENCE 292 AA; 31584 MW; 29FA3CB8FCE1D662 CRC64;
PREAPPGVMP VILGEVSVLT TPLSLVRLLA ITFGCAVFSL VAADDPGGSP FKIFCMFTWC
FFFTMTVLIL LVEFIQFQSL VPLSWKNLPI TVATLAALMT LTASIGFPWL VLPPAVSGRM
VAATVFSCLT FLAYITEAYL LKVGSSEQRG YMASAPGLLK VFQVFGGCVI FVAVVDHDRR
AAYFWWCLAV YCCCFLMSLG TILVMLGDCA GRCPLPFSRV LAAFSSLSVL LYVTATVFWV
TAVLGPGPQN QNPNPNPSQP RPGLIMSTVM TCLNLLAYTV DLAFSIKLCA RA
//
