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Database: UniProt
Entry: W5NQS3_SHEEP
LinkDB: W5NQS3_SHEEP
Original site: W5NQS3_SHEEP 
ID   W5NQS3_SHEEP            Unreviewed;       465 AA.
AC   W5NQS3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   28-MAR-2018, entry version 27.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000000513};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000000513, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000000513, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000000513};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000000513}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC   -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit
CC       (TC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
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DR   EMBL; AMGL01073821; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073823; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073824; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073825; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073827; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01073828; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOART00000000541; ENSOARP00000000513; ENSOARG00000000505.
DR   GeneTree; ENSGT00830000128247; -.
DR   OMA; TETEEWQ; -.
DR   OrthoDB; EOG091G0TKO; -.
DR   Proteomes; UP000002356; Chromosome 3.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR005447; VDCC_N_a1su.
DR   InterPro; IPR002077; VDCCAlpha1.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR10037:SF161; PTHR10037:SF161; 1.
DR   Pfam; PF00520; Ion_trans; 2.
DR   PRINTS; PR00167; CACHANNEL.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|RuleBase:RU003808};
KW   Calcium channel {ECO:0000256|RuleBase:RU003808};
KW   Calcium transport {ECO:0000256|RuleBase:RU003808};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Ion channel {ECO:0000256|RuleBase:RU003808};
KW   Ion transport {ECO:0000256|RuleBase:RU003808};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU003808};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003808}.
FT   TRANSMEM     20     43       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    172    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    198    215       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    297    319       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    375    397       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        2     54       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      170    406       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       51     71       {ECO:0000256|SAM:Coils}.
FT   COILED      400    426       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   465 AA;  52480 MW;  C41A7CFB53B76044 CRC64;
     MEGWTDILYN TNDAAGNTWN WLYFLPLIII GSFFMLNLVL GVLSGEFAKE RERVENRRAF
     LKLRRQQQIE RELNGYLEWI FKAEEVMLAE EDKNAEEKSP LDVLKRAAAK RSRNDLIHAE
     EGEGRSADLC AVGSPFARAS LKSGKTESSS YFRRKEKMFR FFIRRLVKAQ SFYWAVLCVV
     ALNTLCVAIV HYQQPQRLTT ALYFAEFVFL GLFLAEMALK MYGLGPRSYF RSSFNCFDFG
     VIVGSIFEVV WAAIKPGTSF GISVLRALRL LRIFKVTKYW SSLRNLVVSL LNSMKSIISL
     LFLLFLFIVV FALLGMQLFG GQFNFQDETP TTNFDTFPAA ILTVFQILTG EDWNAVMYHG
     IESQGGVSKG MFSSVYFIVL TLFGNYTLLN VFLAIAVDNL ANAQELTKDE EEMEEAANQK
     LALQKAKEVA EVSPMSAANI SIAAFVKQTR GTVTRSSSVS SVNSP
//
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