ID W5NRU8_SHEEP Unreviewed; 158 AA.
AC W5NRU8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=TIL domain-containing protein {ECO:0000259|Pfam:PF01826};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000000888.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000000888.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000000888.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000000888.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01089809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NRU8; -.
DR SMR; W5NRU8; -.
DR STRING; 9940.ENSOARP00000000888; -.
DR PaxDb; 9940-ENSOARP00000000888; -.
DR Ensembl; ENSOART00000000921.1; ENSOARP00000000888.1; ENSOARG00000000863.1.
DR eggNOG; KOG1216; Eukaryota.
DR HOGENOM; CLU_1673375_0_0_1; -.
DR OMA; RSCKGHP; -.
DR Proteomes; UP000002356; Chromosome 4.
DR Bgee; ENSOARG00000000863; Expressed in epididymis and 7 other cell types or tissues.
DR CDD; cd19941; TIL; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR PANTHER; PTHR11339:SF396; SCO-SPONDIN; 1.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 2..52
FT /note="TIL"
FT /evidence="ECO:0000259|Pfam:PF01826"
FT REGION 109..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 158 AA; 17043 MW; 43C7BD9BB948D661 CRC64;
MEVVSCAHPC PRRCSDLQEG IVCQRARACL QGCRCPEGSL EQDGGCVPLE HCECTDAQGH
SWAPGSQHQE ACNNCTCRAG QLSCTAQPCP PPAHCAWSRW SAWSPCSRSC GPAGQQSRFR
SSTSGSWAPE CREEQSQSQP CPQPPCPPLC LQGTRPRS
//
