ID W5NSE8_SHEEP Unreviewed; 549 AA.
AC W5NSE8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=DnaJ homolog subfamily C member 1 {ECO:0008006|Google:ProtNLM};
GN Name=DNAJC1 {ECO:0000313|Ensembl:ENSOARP00000001088.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000001088.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000001088.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000001088.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000001088.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01024325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01024326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01024327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01024328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01024329; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NSE8; -.
DR SMR; W5NSE8; -.
DR STRING; 9940.ENSOARP00000001088; -.
DR PaxDb; 9940-ENSOARP00000001088; -.
DR Ensembl; ENSOART00000001122.1; ENSOARP00000001088.1; ENSOARG00000001045.1.
DR eggNOG; KOG0724; Eukaryota.
DR OMA; LLMCGTA; -.
DR Proteomes; UP000002356; Chromosome 13.
DR Bgee; ENSOARG00000001045; Expressed in adrenal cortex and 54 other cell types or tissues.
DR ExpressionAtlas; W5NSE8; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd00167; SANT; 2.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR44653; DNAJ HOMOLOG SUBFAMILY C MEMBER 1; 1.
DR PANTHER; PTHR44653:SF2; DNAJ HOMOLOG SUBFAMILY C MEMBER 1; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..45
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 46..549
FT /note="DnaJ homolog subfamily C member 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004867997"
FT TRANSMEM 152..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..127
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT DOMAIN 484..538
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 487..542
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 394..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 252..279
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 436..472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 63171 MW; 6F8F2791575189CC CRC64;
MTAPCSRLAR LPPRRRPGLV PFPPPRPPPL LLLLLLLAAA GPAHGWESGD LELFDLVEEV
QLNFYQFLGV QQDASSADIR KAYRKLSLTL HPDKNKDENA ETQFRQLVAI YEVLKDDERR
QRYDDILING LPDWRQPVFY YRRVRKMSNA ELALLLFIIL TVGHYAVVWS IYLEKQLIKD
ELLSRKKREK KKKTGGKTVD VSKLGASEKN ERLLVKPQWH DLLPCKLGIW FCLTLKALPH
LIQYSGCFSL SFKYKETRLK EKEDELTRAE LETLQKQKKV KIKKPKPEFP VYTPLESTYI
QSYDHGTSIE EIEEQMDDWL ENRNRTQKKQ APEWTEEDLS QLTRSMVKFP GGTPGRWEKI
AHELGRSVTD VTTKAKQLKD SVTCSPGMVR LSELRSTAQS PRPTRPSAAL PDSIITQREE
AQSATEEEEA AAEPGAEAAE ESRPRRRRPA RPPEPEERVR GKRQKDFDPS EQQSSDEESQ
QSARARAAEG PWTQNQQKLL ELALQQYPRG SSDRWDKIAK CVPSKSKEDC IARYKLLVEL
VQKKKQARS
//
