ID W5NT46_SHEEP Unreviewed; 309 AA.
AC W5NT46;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=AIG1-type G domain-containing protein {ECO:0000259|PROSITE:PS51720};
GN Name=LOC101122778 {ECO:0000313|Ensembl:ENSOARP00000001336.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000001336.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000001336.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000001336.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000001336.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR EMBL; AMGL01089832; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004008213.2; XM_004008164.3.
DR AlphaFoldDB; W5NT46; -.
DR Ensembl; ENSOART00000001376.1; ENSOARP00000001336.1; ENSOARG00000001288.1.
DR Proteomes; UP000002356; Chromosome 4.
DR Bgee; ENSOARG00000001288; Expressed in jejunum and 34 other cell types or tissues.
DR ExpressionAtlas; W5NT46; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF180; GTPASE IMAP FAMILY MEMBER 5; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 285..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..228
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
SQ SEQUENCE 309 AA; 34389 MW; 2B5F346595A7416A CRC64;
MEGLQRSRYG TMAEGGIEHQ GFEPSSSLRI ILVGKTGSGR SATGNSILCQ PVFESKLGAQ
SVTRKCQRAT GMWNGRSILV VDTPPIFEAG AQDQEMYENI GACYLLSVPG PHVLLLVTQL
GRFTEQDVVA VTRVKEVFGA GAERYMVILF THKEDLAGGS LDEYVANTDN LRLRSLVREC
GRRYCAFNTR ASGDEQREQL AQLMAVIEGL EREHQGAFLT NDLFFDAQML WQMGGGACGE
DQRRYLDKVR LQVAKQKQDL KEAERNCVFK ALLRLKAWIV SHTKIFVLLV LCLLIFLAIV
IILCSIHQG
//
