ID W5NU18_SHEEP Unreviewed; 344 AA.
AC W5NU18;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=AIG1-type G domain-containing protein {ECO:0000259|PROSITE:PS51720};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000001662.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000001662.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000001662.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000001662.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGL01089880; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NU18; -.
DR SMR; W5NU18; -.
DR STRING; 9940.ENSOARP00000001662; -.
DR PaxDb; 9940-ENSOARP00000001662; -.
DR Ensembl; ENSOART00000001705.1; ENSOARP00000001662.1; ENSOARG00000001589.1.
DR eggNOG; ENOG502RB0C; Eukaryota.
DR HOGENOM; CLU_010468_1_1_1; -.
DR OMA; KESKARW; -.
DR Proteomes; UP000002356; Chromosome 4.
DR Bgee; ENSOARG00000001589; Expressed in mesenteric lymph node and 50 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF180; GTPASE IMAP FAMILY MEMBER 5; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 320..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..263
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
SQ SEQUENCE 344 AA; 38261 MW; 909DEC42D862D914 CRC64;
LVAARMYLEL HKATCLRTPI RTLALIPFFF LFQKLMEGLQ RSRYGTMAEG GIEHQGFEPS
SSLRIILVGK TGSGRSATGN SILCQPVFES KLGAQSVTRK CQRATGMWNG RSILVVDTPP
IFEAGAQDQE MYENIGACYL LSVPGPHVLL LVTQLGRFTE QDVVAATRVK EVFGVGAERH
MVILFTHKED LAGGSLDEYV ANTDNLRLRS LVRECGRRYC AFNNRASGDE QREQLAQLMA
VIEGLEREHQ GAFLTNELFF DAQMLRQMGG GAHGEGQRHY LDKVRLQVAK QKQGLKEAER
NGASKALLQL KAWIVSHVKI FVLLVLCLFI FLAIVIILCN THQG
//
