ID W5P0J4_SHEEP Unreviewed; 306 AA.
AC W5P0J4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=EamA domain-containing protein {ECO:0000259|Pfam:PF00892};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000003942.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000003942.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000003942.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000003942.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01063422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5P0J4; -.
DR STRING; 9940.ENSOARP00000003942; -.
DR PaxDb; 9940-ENSOARP00000003942; -.
DR Ensembl; ENSOART00000004012.1; ENSOARP00000003942.1; ENSOARG00000003697.1.
DR eggNOG; KOG4510; Eukaryota.
DR HOGENOM; CLU_032828_1_2_1; -.
DR OMA; FSLMTVC; -.
DR Proteomes; UP000002356; Chromosome 22.
DR Bgee; ENSOARG00000003697; Expressed in abomasum and 53 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR PANTHER; PTHR22911:SF127; SOLUTE CARRIER FAMILY 35 MEMBER G1; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..142
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 164..292
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 306 AA; 33824 MW; 7A22D2638504680E CRC64;
EAEKKAPCPG LGLFYTLLSA FLFSVGSLFV KKVQDIHAVE ISAFRCVFQM LIIIPCLIYR
KTGFIGPKGQ RIYLLLRGVL GSNAMILLYY AYQLTSLADA TVISFSCPVF TSIIACVFLK
EKYSPWDALF TAFTITGVIL IVRPPFLFGS EIAETDKDYS VHVKGALVAL AHAVFAAMTL
VILRKIGTSV DYMLSIWYYV IVGLIECVIV LSILGEWRLP HCGLDRLFLI LIGMFGLGGQ
MFLAKALQIE KAGPVALMKT MDVVFAFIFQ IIFFNDMPSW WTVGGSLCVI ASSTGAAIRK
WCQSTK
//
