ID   W5P2S6_SHEEP            Unreviewed;      1394 AA.
AC   W5P2S6;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Protein strawberry notch homolog 1 {ECO:0008006|Google:ProtNLM};
GN   Name=SBNO1 {ECO:0000313|Ensembl:ENSOARP00000004726.1};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000004726.1, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000004726.1, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000004726.1,
RC   ECO:0000313|Proteomes:UP000002356};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA   Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000004726.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SBNO family.
CC       {ECO:0000256|ARBA:ARBA00006992}.
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DR   EMBL; AMGL01039169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9940.ENSOARP00000004726; -.
DR   PaxDb; 9940-ENSOARP00000004726; -.
DR   Ensembl; ENSOART00000004807.1; ENSOARP00000004726.1; ENSOARG00000004404.1.
DR   eggNOG; KOG1513; Eukaryota.
DR   HOGENOM; CLU_000212_2_2_1; -.
DR   OMA; CEIGLRT; -.
DR   Proteomes; UP000002356; Chromosome 17.
DR   Bgee; ENSOARG00000004404; Expressed in thymus and 54 other cell types or tissues.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR026937; SBNO_Helicase_C_dom.
DR   InterPro; IPR026741; SNO.
DR   InterPro; IPR039187; SNO_AAA.
DR   PANTHER; PTHR12706:SF8; PROTEIN STRAWBERRY NOTCH HOMOLOG 1; 1.
DR   PANTHER; PTHR12706; STRAWBERRY NOTCH-RELATED; 1.
DR   Pfam; PF13872; AAA_34; 1.
DR   Pfam; PF13871; Helicase_C_4; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT   DOMAIN          254..559
FT                   /note="Strawberry notch AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13872"
FT   DOMAIN          873..1149
FT                   /note="Strawberry notch helicase C"
FT                   /evidence="ECO:0000259|Pfam:PF13871"
FT   REGION          21..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          688..841
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        699..722
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        745..763
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        801..841
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1394 AA;  154415 MW;  3798C4C917E4E925 CRC64;
     MVEPGQDLLL AALSESGISP NDLFDIDGGD AGLATPTPTP PIQQSVPLSA LELGLETEAA
     VPVKQEPETV PTPALLNVRQ PPSTTTFVLN QINQLPTLGS TIVMTKTPPV TTTRQTITLT
     KFIQTTANTR PSVSAPAVRN AMTSAPSKDQ VQLKDLLKNN SLNELMKLKP PANIAQPVAT
     AATDVSNGTV KKESSNKEVA RIWINDMKMR SFSPTMKVPV VKEEDEPEEE DEEEMGHAET
     YAEYMPIKLK IGLRHPDAVV ETSSLSSVTP PDVWYKTSIS EETIDNGWLS ALQLEAITYA
     AQQHETFLPN GDRAGFLIGD GAGVGKGRTI AGIIYENYLL SRKRALWFSV SNDLKYDAER
     DLRDIGAKNI LVHSLNKFKY GKISSKHNGS VKKGVIFATY SSLIGESQSG GKYKTRLKQL
     LHWCGDDFDG VIVFDECHKA KNLCPVGSSK PTKTGLAVLE LQNKLPKARV VYASATGASE
     PRNMAYMNRL GIWGEGTPFR EFSDFIQAVE RRGVGAMEIV AMDMKLRGMY IARQLSFTGV
     TFKIEEVLLS QSYVKMYNKA VKLWVIARER FQQAADLIDA EQRMKKSMWG QFWSAHQRFF
     KYLCIASKVK RVVQLAREEI KNGKCVVIGL QSTGEARTLE ALEEGGGELN DFVSTAKNRG
     VLQSLIEKHF PAPDRKKLYS LLGIDLTAPS NSSSPRDSPC KENKTKKRKG EEINREAKKA
     RKIGGLTGSS SDDSGSESDA SDNEESDYES SKNMSSGDDD DFNPFRDESS EDDEDDPWLI
     RKDHKKNKDR KKRKSIDPDS IQSALLASGL GSKRPSFSST PVISPAPNSA PANSNTNSNS
     SLITSQDAVE RAQQMKKDLL DKLEKLAEDL PPNTLDELID ELGGPENVAE MTGRKGRVVS
     NDDGSISYES RSELDVPVEI LNITEKQRFM DGDKNIAIIS EAASSGISLQ ADRRAKNQRR
     RVHMTLELPW SADRAIQQFG RTHRSNQVTA PEYVFLISEL AGEQRFASIV AKRLESLGAL
     THGDRRATES RDLSRFNFDN KYGRNALEIV MKSIVNLDSP MVSPPPDYPG EFFKDVRQGL
     IGVGLINVED RSGILTLDKD YNNIGKFLNR ILGMEVHQQN ALFQYFADTL TAVVQNAKKN
     GRYDMGILDL GSGDEKVRKS DVKKFLTPGY STSGHVELYT ISVERGMSWE EATKIWAELT
     GPDDGFYLSL QIRNNKKTAI LVKEVNPKKK LFLVYRPNTG KQLKLEIYAD LKKKYKKVVS
     DDAVVHWLDQ YNSSADTCTH AYWRGNCKKA SLGLVCEIGL RCRTYYVLCG SVLSVWTKVE
     GVLASVSGTN VKMQIVRLRT EDGQRIVGLI IPANCVSPLI NLLSTSDQSQ QLAVQQKQLW
     QQRHPQSIAS LSST
//