ID W5P3F9_SHEEP Unreviewed; 125 AA.
AC W5P3F9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=KRAB domain-containing protein {ECO:0000259|PROSITE:PS50805};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000004959.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000004959.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000004959.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000004959.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01028676; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5P3F9; -.
DR STRING; 9940.ENSOARP00000004959; -.
DR PaxDb; 9940-ENSOARP00000004959; -.
DR Ensembl; ENSOART00000005043.1; ENSOARP00000004959.1; ENSOARG00000004637.1.
DR eggNOG; KOG1721; Eukaryota.
DR OMA; THPCEMQ; -.
DR Proteomes; UP000002356; Chromosome 14.
DR Bgee; ENSOARG00000004637; Expressed in testis and 7 other cell types or tissues.
DR ExpressionAtlas; W5P3F9; baseline.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF143; ZINC FINGER PROTEIN 747; 1.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..97
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
SQ SEQUENCE 125 AA; 13910 MW; F026923460AA4651 CRC64;
FPLSSSWQGS ITFEDVAVYF SWEEWALLDK AQKLLYCDAM LENFALMASL GYWHGGEDEE
APSGQSVSVE GMSQVRTPKA GPFPYEAHSC EVCVSILKDI LHLAEERGTH PKQKPFTYGA
CGKPF
//
