ID W5P519_SHEEP Unreviewed; 355 AA.
AC W5P519;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=MYND-type domain-containing protein {ECO:0000259|PROSITE:PS50865};
GN Name=PDCD2 {ECO:0000313|Ensembl:ENSOARP00000005522.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000005522.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000005522.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000005522.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000005522.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGL01109161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01109162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5P519; -.
DR STRING; 9940.ENSOARP00000005522; -.
DR PaxDb; 9940-ENSOARP00000005522; -.
DR Ensembl; ENSOART00000005609.1; ENSOARP00000005522.1; ENSOARG00000005152.1.
DR eggNOG; KOG2061; Eukaryota.
DR HOGENOM; CLU_034893_2_0_1; -.
DR OMA; HQVIRYS; -.
DR Proteomes; UP000002356; Chromosome 8.
DR Bgee; ENSOARG00000005152; Expressed in mesenteric lymph node and 51 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR007320; PDCD2_C.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR12298; PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED; 1.
DR PANTHER; PTHR12298:SF4; PROGRAMMED CELL DEATH PROTEIN 2; 1.
DR Pfam; PF04194; PDCD2_C; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 146..183
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 25..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..72
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 39492 MW; AC69429DAFB792F4 CRC64;
MASPSAGPAE LGFVEAVPSW RLRSEQFPSK VGGRPPPAGL SPQEAARPPP YPAGLSPQEA
ARPPPYPAGL FPPEPREHLR GGGRPACSLT SSRQPSGSRC ARVLSVFRNQ LPRRNDFYSY
EPPSEDPPSE TGESVHLQLK SGAHLCRVCG CSGPKRCSRC HKAHYCSKEH QSLDWRLGHK
QACAQTDNLD STVPDHNFLF PEFEIVIETE DEIMPEAVER DDESEIIGTM GEAHEEELES
MAKHESREDR IFQKFKTKIS PEPEQILRYG RGVAPLWISG ENIPQEKDIP DCPCGAKRLF
EFQVMPQLLN YLKADRLGRS VDWGVLAIFT CAESCKLGIG YTEEFVWKQD ITDAA
//
