ID W5P964_SHEEP Unreviewed; 420 AA.
AC W5P964;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Serpin domain-containing protein {ECO:0000259|SMART:SM00093};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000006972.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000006972.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000006972.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000006972.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR EMBL; AMGL01067638; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5P964; -.
DR SMR; W5P964; -.
DR STRING; 9940.ENSOARP00000006972; -.
DR PaxDb; 9940-ENSOARP00000006972; -.
DR Ensembl; ENSOART00000007079.1; ENSOARP00000006972.1; ENSOARG00000006513.1.
DR eggNOG; KOG2392; Eukaryota.
DR HOGENOM; CLU_023330_0_2_1; -.
DR OMA; IHHQFQK; -.
DR Proteomes; UP000002356; Chromosome 23.
DR Bgee; ENSOARG00000006513; Expressed in rumen and 12 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF161; SERPIN B13; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 51..420
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
FT COILED 99..126
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 420 AA; 47236 MW; 5DF8C7F0C94CD1CE CRC64;
RGRESYKLKT SPARLAQASW FLALSPLSFQ KPGPAGIIMD SLLPASARFG LDLFKDLSKT
DEGNILFSPA GISTTIGMLP PVTRGAAATQ EQEVPFFEKD TESSRIKAEE TELEATEEMH
RQLQRVLSEI SKPSDDYELK IANRLFGEKT YLFLQKYLDY VEKHYHASLE PVDFVNAADE
SRKKINSWVE SQTNEKIKDL LPDGSLSSSI KLVVVNVIYF KGQWDREFKK ENTKEEEFWL
NKSTSKSVLM MTQRQSFSFK TLEDVPAKIL GLPYRNHDLS MFLLLPNDID GLEKIIDKIT
PETLIEWTSV GRMEERAVDL HLPRFRVAGT YDLEATSAGL CAAGLSGSPE GAGLRAQRLL
HRSVLELTEA GTEAAAATAV GFAVTPAQDW ERFHCNHPFL FFIRHNKSDS VLFFGRFSSP
//
