ID W5PAI1_SHEEP Unreviewed; 1154 AA.
AC W5PAI1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=A-kinase anchor protein 2 C-terminal domain-containing protein {ECO:0000259|Pfam:PF15304};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000007441.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000007441.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000007441.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000007441.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01047244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047245; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047246; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047247; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047249; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047250; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047252; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01047253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PAI1; -.
DR STRING; 9940.ENSOARP00000007441; -.
DR PaxDb; 9940-ENSOARP00000007441; -.
DR Ensembl; ENSOART00000007552.1; ENSOARP00000007441.1; ENSOARG00000006946.1.
DR eggNOG; ENOG502QR7I; Eukaryota.
DR HOGENOM; CLU_007780_0_0_1; -.
DR OMA; RDNCSAN; -.
DR Proteomes; UP000002356; Chromosome 2.
DR Bgee; ENSOARG00000006946; Expressed in lung and 54 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:InterPro.
DR InterPro; IPR029304; AKAP2_C.
DR InterPro; IPR004965; Paralemmin.
DR PANTHER; PTHR10498:SF10; PALM2 AND AKAP2 FUSION-RELATED; 1.
DR PANTHER; PTHR10498; PARALEMMIN-RELATED; 1.
DR Pfam; PF15304; AKAP2_C; 1.
DR Pfam; PF03285; Paralemmin; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 1004..1146
FT /note="A-kinase anchor protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF15304"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 878..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..276
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..394
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..569
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..923
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1057
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1081
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1154 AA; 126632 MW; B39077AB3D47C6B8 CRC64;
MEINVEKDKQ TGETKTLSTS TIGPEGVHQR GVKVFDDGTK VVYEVHSGGT VVENGVHTLS
SKDVEELIQK AGQSSLRGGH VSERTGIADG SLSHPKEHML CKEAKLEMVH KSRKDHSSGN
PGQQAPAPST EGPEANLDQP VTMIFMGYQN IEDEEETKKV LGYDETIKAE LVLIDEDDEK
SLREKTVTDV STIDGNAAEL VSGRPISDTT EPSSPEGKEE SLATEPAPGV GWESVLLTRD
DITSEAIASS SADMTVKKPP ELSEDDTRLK HERDNCSAKA LESITSSLPP DHKNMEIEVS
VAECKSVPGI TSTPHSMDHP SPFYSTPHNG LLADHHESLD NDVAREIRYL DEVLEANCCD
STVDGTYNGT SSPEPAAAIL AGSPPPPPPR PAQPEATERA AGRQAPPHLE LHQSDSDTMA
EGRRANGHPP EQPRDVLGDS LQVPVSPSSS TSSRCSSRDG EVTLTTLKKE AKFELRAFHE
DKKPSKLFED DESEKEQYRV RKVRPSEEML ELEKERRELI RSQAVKKNPG IAAKWWNPPQ
EKTIEEQLDE EHLESHKKYK ERKERRAQQE QLLMQQQQQQ QQQQQPPPQL CTAPASSRER
PSVTDHPKED IVTEQIDFSA ARKQFQQMEN SRQTVARGQS TPRLFSIKPF YKPLGSINSD
KTLTISRPAS IGAPPEDSSA AKGQKAHCAP ESQSSGGGAQ GSTAPQGKEG PYSEPSKRGP
LSKLWADDSE FTSVRAVLTV VKDDDPGILD QFSRSVNVSL TQEELDSGLD ELSVRSQDTT
VLETLSNDFS MDNISDSGAS NETTNALQEN SLADFSLPQT PQTDNPSEGR GEGVSKSFSD
HGFYSPLSTL GDSASVDDPL EYQAGLLVQN AIQQAIAEQV DRAGSETTKG GPEQQGPQTS
QEKASPKAPS SEKPQSMFEP PQVSSPVQEK RDVLPKILST EDRALRERGP SQPLPVVQPS
GPINMEETRP EGSYFSKYSE AAELRSTASL LATQESDVMV GPFKLRSRKQ RTLSMIEEEI
RAAQEREEEL KRQRQVLQST QSPKAKNAPS LPSRTSCYKT APGKIEKVKP PPSPTPEGPS
LQPDLAPEEA AGSQRPKNLM QTLMEDYETH KSKRRERMDD SSVLEATRVN RRKSALALRW
EAGIYANQEE EDNE
//
