ID W5PBF6_SHEEP Unreviewed; 1089 AA.
AC W5PBF6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000007767.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000007767.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000007767.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000007767.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01066539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066540; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066542; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066543; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066546; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01066548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PBF6; -.
DR Ensembl; ENSOART00000007883.1; ENSOARP00000007767.1; ENSOARG00000007246.1.
DR HOGENOM; CLU_004018_0_0_1; -.
DR OMA; HCESAFS; -.
DR Proteomes; UP000002356; Chromosome 23.
DR Bgee; ENSOARG00000007246; Expressed in cerebellum and 50 other cell types or tissues.
DR ExpressionAtlas; W5PBF6; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406:SF8; C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF13912; zf-C2H2_6; 5.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 25.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 22.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 21.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 42..69
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 70..97
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 98..125
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 126..153
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 170..198
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 205..233
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 234..261
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 361..389
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 401..429
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 437..460
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 558..580
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 588..610
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 618..642
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 646..674
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 676..704
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 707..734
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 733..756
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 810..837
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 854..881
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 883..910
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1044..1072
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1089 AA; 122279 MW; 9E4CE9CF830A267B CRC64;
DVEDDPTCSW PASSPSSKDQ TSPSHGEGCD FGEEEGGPGL PYPCQFCDKS FSRLSYLKHH
EQSHSDKLPF KCTYCSRLFK HKRSRDRHIK LHTGDKKYHC SECDAAFSRS DHLKIHLKTH
TSNKPYKCAI CRRGFLSSSS LHGHMQVHER NKDGSQSGSR LEDWKMKDTQ KCSQCEEGFD
FPEDLQKHIA ECHPECSPNE DRAALQCVYC HELFVEETSL MNHMEQMHGG EKKNSCSICS
ESFHSVEELY SHMDSHQQPE SCNHSNSPSL VTVGYTSVSS TTPDSNLSVD SSTMVEAAPP
IPKSRGRKRA AQQTPDMTVP SSKQAKVTYS CIYCNKQLFS SLAVLQIHLK TMHLDKPEQA
HICQYCLEVL PSLYNLNEHL KQVHEAQDPG LIVSALPAIV YQCNFCSEVV NDLNTLQEHI
RCSHGFANPA AKDSNAFFCP HCYMGFLTDS SLEEHIRQVH CDLSGSRFGS PVLGTPKEPV
VEVYSCSYCT NSPIFNSVLK LNKHIKENHK NIPLALNYIH NGKKSRALSP LSPVAIEQTS
LKMMQAVGGA PARQAGEYIC NQCGAKYTSL DGFQTHLKTH LDTVLPKLTC PQCNKEFPNQ
ESLLKHVTIH FMITSTYYIC ESCDKQFTSV DDLQKHLLDM HTFVFFRCTL CQEVFDSKVS
IQLHLAVKHS NEKKVYRCTS CNWDFRNETD LQLHVKHNHL ENQGKVHKCI FCGESFGTEV
ELQCHITTHS KKYNCQFCSK AFHAIILLEK HLREKHCVFD TKTPNCGANG ASEPGQKEEV
ELQTLLTNSQ ESHNSHDGSE EDVDTSEPMY GCDICGAAYT METLLQNHQL RDHNIRPGES
AIVKKKAELI KGNYKCNVCS RTFFSENGLR EHMQTHLGPV KHYMCPICGE RFPSLLTLTE
HKVTHSKSLD TGNCRICKMP LQSEEEFLEH CQMHPDLRNS LTGFRCVVCM QTVTSTLELK
IHGTFHMQKT GNGATVQATG RGPHVPKLYK CASCLKEFRS KQDLVKLDIN GLPYGLCAGC
VNLSKSASPG VSLAPGSSRP GLGTRCSSCN VKFESESELQ NHIQTVHREL VPDSNSTQLK
TPQVSPMPR
//
