ID W5PCG4_SHEEP Unreviewed; 488 AA.
AC W5PCG4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000008126.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000008126.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000008126.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000008126.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000008126.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGL01028963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01028964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01028965; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PCG4; -.
DR SMR; W5PCG4; -.
DR STRING; 9940.ENSOARP00000008126; -.
DR PaxDb; 9940-ENSOARP00000008126; -.
DR Ensembl; ENSOART00000008247.1; ENSOARP00000008126.1; ENSOARG00000007575.1.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_001570_22_3_1; -.
DR OMA; MFSWFLR; -.
DR Proteomes; UP000002356; Chromosome 14.
DR Bgee; ENSOARG00000007575; Expressed in omasum and 47 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11026; CYP2; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24300:SF23; CYTOCHROME P450 2S1; 1.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 288..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 488 AA; 53704 MW; C9AB0EDF5082AB00 CRC64;
VWPLSVCVCL YIYILFFFLF QLPFHSAPAP GAQPLPLLGN LLQLRPGALY LGLLRLSKKY
GPVFTVYLGP WRRVVVLVGH EAVQEALGGQ AEEFSGRGMV ATLDRTFDSH GVFFSNGERW
RQLRKFTTLA LRDLGMGKRE GEELIQAEAR CLVEALQGTK GQLFDPSLLL AQATCNIICS
LVFDLRLPYD SEEFQAVVRA AGGIAVAVSS PWGQTYEMFS RFLQCLPGPH TQLLGHLGTV
AAFAAQQGGQ HEGSLGAAGP ARDLMDAFLL KMAKEKQDPN TEFTAKNLLM TVVYLLFAGT
VTVSTTIRYT LLLLLKYPQV QERVQEELMR ELGAGQGPSL EDRARLPYTD AEGAGLLALV
PMGIPRALTK TTRFRGYTLP QGTEVFPLLG SVLHDPAVFK EPEEFNPGRF LDADGKFKKH
EAFLPFSLGK RVCLGEGLAR TELFLLFTAI LQAFSLEGPC PPGALSLQPA ISGLFNIPRA
FQLRFRPR
//
