ID W5PEW7_SHEEP Unreviewed; 3078 AA.
AC W5PEW7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 12-AUG-2020, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000008982};
GN Name=CENPF {ECO:0000313|Ensembl:ENSOARP00000008982};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000008982, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000008982, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000008982,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000008982}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2014) to UniProtKB.
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DR EMBL; AMGL01022632; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01022633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSOART00000009112; ENSOARP00000008982; ENSOARG00000008368.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000002356; Chromosome 12.
DR ExpressionAtlas; W5PEW7; baseline.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1889..2007
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2095..2234
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2277..2416
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2934..2977
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 211..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 808..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1243..1265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1526..1546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1663..1689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1714..1748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2856..3078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 523..706
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 725..752
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 839..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..957
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 969..989
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1036..1056
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1089..1109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1118..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1284..1325
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1395..1422
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1547..1617
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1790..1817
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1825..1852
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1886..1913
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1949..2042
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2071..2098
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2106..2242
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2260..2280
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2288..2431
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2439..2567
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2582..2641
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2653..2680
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2703..2789
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2800..2827
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 475..493
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1530..1544
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1669..1689
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2856..2870
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2882..2896
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2904..2918
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2919..2935
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2963..2977
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2992..3042
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3078 AA; 352863 MW; 470D5035D0766A0F CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKIENEKT
EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSLN SCLTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQAIPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS NTLKTPVRRD
FSASHFSGEQ EVTPSRSTLQ IGKTDANSSF CDNSSNSHLL DQLKAQNQEL RSKISELELR
LQGQEKEMKG QVNKLQELQL QLEKAKVELN EKEKVLNKTR DELVRTTSQY DQASTKCTAL
EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECTQMKAR
LTQELQQAKN TYNILQAELD KVTSVKHQVE KKLEEFKQNL SKTEQALQAS QTKENELRRS
SEEMKRENSL LKSQSEQRAR EVCHLEEELK KAKQCLSQSQ NFAEEMKAKN TSQETMLRDL
QEKINQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNEKLSK TERESEALLS
ALELKKKEYE ELKEEKTLFS RWKRENEQLL NQMESEKESL QSKVNHLETC LKTQQIKSHE
YNERVRTLEM ERENLNVEIR NLQNVIDSKT AEAETQKRAY GELQQKAEFS DQKHEKEIEN
MCLKISHLTG QVEDLEHKLQ LLSSEIMGKD QRYQDLHAEY ESLRDLLKSR DSSAVTVEPH
QRSRLAFEQQ SALNNSFASI IGEQESVSSE RSGCHVATDQ SPESSSMLQN RVVSLEFSLE
SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSVHQNVVT
ETLAALESKE RELQFLNEKL ETEQAEIGEL KKNNHLLQES LKELQFLSET LSLEKKELNS
IISLNKKDIE GLTQENGTLK EINATLTREK MNLLQKTESF SNCIDERDKS ISELSNQYKQ
ERLTLLQRCE ETGNAFQDLS EKYKAVQEKN SKLECLLSEC TGVCEDRKNE LGQLKETFAR
EHQAFVSQLA SAEERNQNLI LELETVQQAL QSEITDIQNS SKREADGLKQ EIMKLKEEQN
KMQQEVNALL QENEHLMELM RTKHEHQCLE LEPIQDSEKE GEREINTCHV QLPMDLDVKD
SSLDTYKAQL VQVESEVRNM ELRLQKSEKE ECLQHELQAR ELETEDLQQD TQSQDISSLG
DSEIDPEEKY ISVLHELSTS QQDNAHLQCS LQTAMNKLNE LEKMCEALQV EKSELISELN
DSRSECITAT SKMAEEVGKL VKEVETLNDE NGLLQGESVE ETPEGEFGVQ QDEQTSVNLN
PLDDCNFYEH LTMSNKEVQM HFAELQEKFS SLQSEHKILH EQHCLMSSKM SELQSYVDTL
KAENSVLSMS LRSAQGDLVK EVTPAPGEEH SLSLSFSCVT DSPGNASLGE SSFYKDLLEH
TTETSLLHNL EGTVSANQSS VEEVSCSSLE EENLTEKETP SGPLRSTREL ETLCQTYLQS
LKQLEEEIES QGLTKNKEIE ELKELLSSSR EELDYLRKQY LSENEQWQQK LTDVTAEMES
KLAAEKRHTE HLTLELEVAR LQLQGLDLSS RSLLGTDIED AIPGGNDSCD IRESEEYTSE
PKERTPKHEI HQVCEKDVQQ DLSLEMEKIT KTGAARLTEE WSREQSSEAS PEAPVGDPAQ
GCSECTSELY LPGPNASVPR DVLENQVTIQ SLELKVKETS NENLRLLHGI EERDQKVDNL
LNEIKELDSK FHLLEVQLTT KIEACVALEK IVEELKKEKL DLNEKLASFS CHNQREESSG
GLTPSLEMVT SKLPHEDIED DVAKVTDNWR EKCLQVENEL QRVQSEKDSM EHHTLSAEAS
LEAVQTEKLY LEKDNENKQT VITCLEEGLS VVTSERDQLR GELDTLSKEN QELDQMSEKM
KEKIRELESH QRECLHLQEQ LQSLEKDSQA LSLVRSELEN QIEQLNKEKD SLVWESESLQ
TKLSESENEK LAITKALETA LMEKGEVAVR LSSTQEEVHQ LRKGIEKLRV RIEADEKKQL
HVSEKLKASE RRNDSLQDKV ETLERELQMA EENQELVILD AENCKAEVET LKTQIELTTE
RLKDLESDLV TIRTEKENLV KQLQEKQGQA SELDTLLSSL KNLLEEKERE KIQMKEESKA
AVEMLQTQLR ELSEEVAALC DDQETWKVKE QSLDSPAQEV QQLRNNIEKL KLHLDIDKKQ
QLHILEKLKE SEHQADLLKD TVENLERELK LSGENQEHVT LEAEKSKAEV ETLKATAKEM
DQNLRGLQLD LVNIRSEKED LTKELLKEQS RVSELQTLNS SFENLLREKE QEKVQMKEES
KAAVEMLQTQ LKELNEKMAA LGNDQETWKV KEQSLSSQVD SLEHEKAQLL QGLDDAKSNY
MILQSSVNDL IQEVEDGKQK LEKKDEEISI LESQTRDQEQ LVSKLSQMEG EQQLWKKQKA
DLENLMVELE QKIQVLQSKN DALQDTLEAL QNSYRNLEKE LELTNLEKTS FVEKVNTMTV
KETELQKEMH AMIQKTAELK EEFSGEKNRL TEELNLMLEE VKSSKGQLNE LMLENSELKK
SLDCVHKDHM EEQGKMRGEI AEYQLRLQEA ENKHQALLLD TNKQHEMEIQ TYREKLTSKE
ECLSSQKVEI DLLKSSKEEL NNSLKATTEI LEELKKTKME NLKHADKLKK ENDRAQSKIK
LLMKSCKQLE EEKVMLQKEL SHLEAAQEKQ RADTVVDANV DELITEMKEL KESLEEKTKE
ADEYLDKYCS LLISHEKLEK AKEMLETQVA RLSSQQSKLN LRSSPLVNSV APGPSPVPSA
TEKKLPSGQN KSSGKRQRSS GIREDGGETT PSTPETFSKK SRKAIKSGTH PPEDAEDAEF
EPEGLPEVVK KGFADIPTGK TSPYILRRTT MATRTSPRLA AQKLAASPLS LDKENLTETS
KPTAGGSRSQ KVKVSQQSPV DSGTTFRDPT ARSLSISNLP ERSPAGSPRE GLRAKRGHHA
PSPEASLQSK GSENCRVQ
//
