ID W5PH78_SHEEP Unreviewed; 348 AA.
AC W5PH78;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000009795.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000009795.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000009795.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000009795.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01087212; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PH78; -.
DR SMR; W5PH78; -.
DR PaxDb; 9940-ENSOARP00000009795; -.
DR Ensembl; ENSOART00000009937.1; ENSOARP00000009795.1; ENSOARG00000009129.1.
DR eggNOG; ENOG502SQHK; Eukaryota.
DR HOGENOM; CLU_077975_3_2_1; -.
DR OMA; PGIQQEI; -.
DR Proteomes; UP000002356; Chromosome 4.
DR Bgee; ENSOARG00000009129; Expressed in major salivary gland and 50 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00099; IgV; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR19256:SF62; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19256; T-CELL RECEPTOR GAMMA CHAIN; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..348
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004868932"
FT TRANSMEM 314..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..122
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 151..246
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 348 AA; 38776 MW; 378D6E854A411B78 CRC64;
MGFSLGAEGR AVLGRLALLW ALVVPGIQQE IRLSQRSVMV GSAGGAMTMP CHVSRSVDYV
HWFRQLEGQA PERLLYLALS KRDVQWDSVL GGDKVSTEDG KSCTMSLRKL AKSDEGLYYC
AAWGSNLNYM IFGGGTKVFV QDKNLPTDII PKPTIFLPSI NEVNHQQTAT YLCLLENFFP
DVIKVSWKEK NGKRVLPSQQ GNTMKTNNTY MKFSWLTVTE DSMKKEHMCV VRLEKNAGGK
DQEILFPAVN EVFSPVVATT EPPDDCLQDE SEVTDTDFTK VCSRGESEVT DSTKACLKDE
NNTVELQLAY NSAYYTYLLL LLKSAIYFVT SSCCVFRRTG VCHDGKSS
//
