ID W5PHI0_SHEEP Unreviewed; 601 AA.
AC W5PHI0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=BING4 C-terminal domain-containing protein {ECO:0000259|SMART:SM01033};
GN Name=WDR46 {ECO:0000313|Ensembl:ENSOARP00000009897.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000009897.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000009897.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000009897.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000009897.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; AMGL01058198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004018797.1; XM_004018748.3.
DR AlphaFoldDB; W5PHI0; -.
DR SMR; W5PHI0; -.
DR STRING; 9940.ENSOARP00000009897; -.
DR PaxDb; 9940-ENSOARP00000009897; -.
DR Ensembl; ENSOART00000010040.1; ENSOARP00000009897.1; ENSOARG00000009215.1.
DR eggNOG; KOG1272; Eukaryota.
DR HOGENOM; CLU_022996_2_0_1; -.
DR OMA; KYTFIYD; -.
DR Proteomes; UP000002356; Chromosome 20.
DR Bgee; ENSOARG00000009215; Expressed in epididymis and 54 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR012952; BING4_C_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040315; WDR46/Utp7.
DR PANTHER; PTHR14085:SF3; WD REPEAT-CONTAINING PROTEIN 46; 1.
DR PANTHER; PTHR14085; WD-REPEAT PROTEIN BING4; 1.
DR Pfam; PF08149; BING4CT; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01033; BING4CT; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 435..516
FT /note="BING4 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01033"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 66750 MW; 5E1E4F2FDA3E36EE CRC64;
METVPKPGSN VPPKKDRLQA KKKKPRRYWE QETTGTAAGA SPGPPHKRKR SRELRPQKPK
RNDTSKKFRI SKKPRELKSP GPQRTFSGAQ DPFAGPAPVS VEVVRKYCRI DKSKELPHAK
TKTRSRLAVA EAQEEETSVR AARSELLLAE EPGFLEGEDG EDTAKIRQAD IVEAVDIASA
AKHFDLNLRQ FGPYRLNYSR TGRHLAFGGR RGHVAALDWV TKKLMCEINV MEAVRDIRFL
HSEALLAVAQ NRWLHIYDNQ GIELHCVRRC DRVTRLEFLP FHFLLATASE TGFLTYLDVS
VGKIVAALNA RAGRLSVMTQ NPYNAVIHLG HSNGTVSLWS PAMKEPLVKI LCHRGGVRAV
AVDSTGMHMA TSGLDHQLKL FDLRGTFQPL STRTLPQGAG HLAFSQRGLL AAGMGDVVNI
WAGQGKASPP SLEQPYLTHR LSGHVHGLQF CPYEDVLGVG HSGGITSMLV PGASRNQLRG
LESNPYRSRK QRQEWEVKAL LEKVPAELIL SGHTAPCLGG CCSFHSPPLP QGYDPDTRAP
FQPKPKQKGR SSTASLVKRK RKVMDQEHRD KVRQSLEQQP QKQEKAKPTG ARPSALDRFV
R
//
