ID W5PJK4_SHEEP Unreviewed; 1301 AA.
AC W5PJK4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=G2/mitotic-specific cyclin-B3 {ECO:0000256|ARBA:ARBA00021434};
GN Name=CCNB3 {ECO:0000313|Ensembl:ENSOARP00000010625.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000010625.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000010625.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000010625.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000010625.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
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DR EMBL; AMGL01115468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_011962091.1; XM_012106701.2.
DR SMR; W5PJK4; -.
DR STRING; 9940.ENSOARP00000010625; -.
DR PaxDb; 9940-ENSOARP00000010625; -.
DR Ensembl; ENSOART00000010782.1; ENSOARP00000010625.1; ENSOARG00000009908.1.
DR GeneID; 101102288; -.
DR CTD; 85417; -.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_006366_0_0_1; -.
DR OMA; RCVHASM; -.
DR OrthoDB; 5474295at2759; -.
DR Proteomes; UP000002356; Chromosome X.
DR Bgee; ENSOARG00000009908; Expressed in embryo and 56 other cell types or tissues.
DR ExpressionAtlas; W5PJK4; baseline.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd20508; CYCLIN_CCNB3_rpt1; 1.
DR CDD; cd20510; CYCLIN_CCNB3_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR048258; Cyclins_cyclin-box.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR PANTHER; PTHR10177:SF601; G2_MITOTIC-SPECIFIC CYCLIN-B3; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 1080..1164
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 1173..1289
FT /note="Cyclin C-terminal"
FT /evidence="ECO:0000259|SMART:SM01332"
FT DOMAIN 1177..1261
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..312
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1301 AA; 148292 MW; 88BC1849CA6AC5EB CRC64;
MPVPLPPQHS KRETRKSQSS IVPSDHEPSE KKDEKYQAKI SPSSPQGPLK KRSAFEDLTN
APQSQHVQPK KEANNEFVKD TSKKRNKERL PENNKMNIKR CKVELSPIIV STTMVPNIID
NLLTLDMSTS SKTPNTEEAS IFKEPFILKE EPTSEDAVLT KRSLSSNKCT NQEVMSLLKK
PLSLQRKSDS DVQPMTFGKK RKTGEAAITN RTLSLKNMCQ YQGKQSCLGE ELALQDVSVE
EDSSFMELQN VRKKAKTEEA TFTNPLSSLK KKYTTQRKMS YRKNPLVLQK TTSEEKPLTE
ESFKRKPTAE EESFFQEPPA LQEKHTSEQE ISILKKSLAF QEKIDTEEKS LFKEPLAFKK
QSTTEETAFT MRPLSLKKKC TTQRKRKMTY TKKTASEEKA LTSQLLSFKK KPTPKEESLF
QDLSVLQEKH TDDGAVTLLK KPWALQKKDD EDDFLMEPLS FRKAHTTKEA TLPKKPLPLK
GKCTTQGKMY HLKNPPVLQN VASEEKSLVK EPLPFKKPPT TKESLFQEPS ALQEKHTILE
EASILKKPLV LQKTPAEEES LKKETLTFKK FTIGEAASTN MLLSLKEKCT TQGKSCLIKP
LVLQTISEEK SLIKEPTTEV ESLLKEPSAL QEKHTTQGDV APLKKPWALQ ERIDSKDEFL
MEPLSFRKTQ TTNVAVSTEE SLSLMKQTCA TQTIMSIWQE LLGLQNMIGK NSVMMPVSSR
KKSSTDEAVL TKTTLSPKMR QITQWNTVIE KTTSEKESLF KKLLPLKKKY TTEEGLLFQD
PSVLKEKHTS LQQVSLSKKP LTLEEKIATK EESNVKELLT MEKSLVLQKT DTKVDFLKTL
LALQKKSTTE EKCFFKKPLV LKENFSPEAA ASIEGQSSFK KQPTAQGEVF LLKKQSTLQE
NITGEEECII KQPQALQEKP SIEKETILRE SLALQDNSMI EKEAVWKEPL ALQKTLTHKE
DPFLKDCTFQ IETSPDVSTT TPESGTGLSN TVTMSCSTIS KSSTCESSSD KPFSSCDKRS
QQEMIPLGNT DIDCSDPLFS SVYAKDIFSY MKKREEKFIL KKYMTRQTDI DSDMRAILVD
WLVEVQMTFE MSHETLYLAV KLVDHYLMKV ICKKDKLQLL GSTAFMIAAK FEERCPPSVN
DFLYICNDIY KRDEMLAMEA SILKILKFDI NIPIAYHFLR RYARCVYASM KTLTLSRFIC
ELTLLEYDYV QERASKLAAA SFFLALCMNK LGHWAPILEY YSGYRISDLH ALVRQLNILL
TFHSCNRLKT VCSKYSHEIF FEVAKIPPLD MLALEKILRC C
//
