ID W5PMQ7_SHEEP Unreviewed; 476 AA.
AC W5PMQ7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=F-box domain-containing protein {ECO:0000259|PROSITE:PS50181};
GN Name=SKP2 {ECO:0000313|Ensembl:ENSOARP00000011732.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000011732.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000011732.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000011732.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000011732.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01035206; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PMQ7; -.
DR SMR; W5PMQ7; -.
DR STRING; 9940.ENSOARP00000011732; -.
DR PaxDb; 9940-ENSOARP00000011732; -.
DR Ensembl; ENSOART00000011900.1; ENSOARP00000011732.1; ENSOARG00000010940.1.
DR eggNOG; KOG2120; Eukaryota.
DR HOGENOM; CLU_032515_2_0_1; -.
DR OMA; MWNRKCR; -.
DR Proteomes; UP000002356; Chromosome 16.
DR Bgee; ENSOARG00000010940; Expressed in embryo and 54 other cell types or tissues.
DR CDD; cd22114; F-box_FBXL1; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR16134; F-BOX/TPR REPEAT PROTEIN POF3; 1.
DR PANTHER; PTHR16134:SF32; S-PHASE KINASE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF12937; F-box-like; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00367; LRR_CC; 5.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 146..192
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
SQ SEQUENCE 476 AA; 53690 MW; 1DE361249C47222F CRC64;
ALLGWNVDRV RGFRCTRSAP HAVRRRAPKR EFGGRAPLQL MHAFKTPEPA DAMHRKHLQE
IPDQSSNVTT SFTWGWDSSK TSELLSGMGV SALEKEEVDS ENIPQELLSN LGHPQSPPRK
WLKSKGDDKD FVIVRRPKLN RENFPGVSWD SLPDELLLGI FSCLCLPELL KVSSVCKRWY
HLAFDESLWQ TVDLAGRNLY PDVVGRLLSR GVVAFRCPRS FMDQPLVEHF SPFRLQHLDL
SNSVIDVSTL QGLLSHCSKL QNLSLEGLRL SDPVVDNLAQ NTNLLRLNLS GCSGFSESAL
KTLLSSCSRL DELNLSWCYD FTEKHVQVAV AHVSETITQL NLSGYRKNLQ RSDVSTLVGR
CPNLVHLDLS DSVMLKNDCF PEFYQLNYLQ HLSLSRCYDI IPETLLELGE IPTLKTLQVF
GIVPDGTLQL LKEALPHLQI NCSHFTTIAR PTIGNKKNQE IWGIKCRLSL EKPSCL
//
